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Heat Shock Protein 90 is overexpressed in high-risk myelodysplastic syndromes and associated with higher expression and activation of Focal Adhesion Kinase
Myelodysplastic syndromes are characterized by a high risk of evolution into acute myeloid leukaemia which can involve activation of signalling pathways. As the chaperone heat shock protein 90 (HSP90) has a key role in signal transduction, we investigated its role in the pathogenesis and evolution o...
Autores principales: | Flandrin-Gresta, Pascale, Solly, Françoise, Aanei, Carmen Mariana, Cornillon, Jérôme, Tavernier, Emmanuelle, Nadal, Nathalie, Morteux, Franck, Guyotat, Denis, Wattel, Eric, Campos, Lydia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717957/ https://www.ncbi.nlm.nih.gov/pubmed/23047954 |
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