Disulfiram, a drug widely used to control alcoholism, suppresses self-renewal of glioblastoma and overrides resistance to temozolomide

Glioblastomas (GBM) are associated with high rates of relapse. These brain tumors are often resistant to chemotherapies like temozolomide (TMZ) and there are very few treatment options available to patients. We recently reported that polo-like kinase-1 (PLK1) is associated with the proliferative sub...

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Detalles Bibliográficos
Autores principales: Triscott, Joanna, Lee, Cathy, Hu, Kaiji, Fotovati, Abbas, Berns, Rachel, Pambid, Mary, Luk, Margaret, Kast, Richard E., Kong, Esther, Toyota, Eric, Yip, Stephen, Toyota, Brian, Dunn, Sandra E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2012
Materias:
Research: Complementary Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717961/
https://www.ncbi.nlm.nih.gov/pubmed/23047041

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