A Discrepancy Between Clinical Course and Magnetic Resonance Imaging in a Case of Non-Herpetic Acute Limbic Encephalitis

We report the case of a 64-year old man who presented memory disturbance, low-grade fever, weight loss, and bilateral hand tremors for three months. He was diagnosed with non-herpetic acute limbic encephalitis (NHALE). Follow-up magnetic resonance imaging (MRI) revealed new lesions after symptomatic...

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Detalles Bibliográficos
Autores principales: Kohno, Naoto, Kawakami, Yuko, Hamada, Chizuko, Toyoda, Genya, Bokura, Hirokazu, Yamaguchi, Shuhei, Takahashi, Yukitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718248/
https://www.ncbi.nlm.nih.gov/pubmed/23888211
http://dx.doi.org/10.4081/ni.2013.e8
Descripción
Sumario:We report the case of a 64-year old man who presented memory disturbance, low-grade fever, weight loss, and bilateral hand tremors for three months. He was diagnosed with non-herpetic acute limbic encephalitis (NHALE). Follow-up magnetic resonance imaging (MRI) revealed new lesions after symptomatic improvement following steroid pulse therapy. This may indicate that there is a time lag between the disturbance or recovery of neurons and astrocytes. Thus, other lesions might occasionally appear during convalescence in patients with NHALE, even if only minimal lesions were found on the initial MRI.

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