A Discrepancy Between Clinical Course and Magnetic Resonance Imaging in a Case of Non-Herpetic Acute Limbic Encephalitis

We report the case of a 64-year old man who presented memory disturbance, low-grade fever, weight loss, and bilateral hand tremors for three months. He was diagnosed with non-herpetic acute limbic encephalitis (NHALE). Follow-up magnetic resonance imaging (MRI) revealed new lesions after symptomatic...

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Autores principales: Kohno, Naoto, Kawakami, Yuko, Hamada, Chizuko, Toyoda, Genya, Bokura, Hirokazu, Yamaguchi, Shuhei, Takahashi, Yukitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718248/
https://www.ncbi.nlm.nih.gov/pubmed/23888211
http://dx.doi.org/10.4081/ni.2013.e8
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author Kohno, Naoto
Kawakami, Yuko
Hamada, Chizuko
Toyoda, Genya
Bokura, Hirokazu
Yamaguchi, Shuhei
Takahashi, Yukitoshi
author_facet Kohno, Naoto
Kawakami, Yuko
Hamada, Chizuko
Toyoda, Genya
Bokura, Hirokazu
Yamaguchi, Shuhei
Takahashi, Yukitoshi
author_sort Kohno, Naoto
collection PubMed
description We report the case of a 64-year old man who presented memory disturbance, low-grade fever, weight loss, and bilateral hand tremors for three months. He was diagnosed with non-herpetic acute limbic encephalitis (NHALE). Follow-up magnetic resonance imaging (MRI) revealed new lesions after symptomatic improvement following steroid pulse therapy. This may indicate that there is a time lag between the disturbance or recovery of neurons and astrocytes. Thus, other lesions might occasionally appear during convalescence in patients with NHALE, even if only minimal lesions were found on the initial MRI.
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spelling pubmed-37182482013-11-22 A Discrepancy Between Clinical Course and Magnetic Resonance Imaging in a Case of Non-Herpetic Acute Limbic Encephalitis Kohno, Naoto Kawakami, Yuko Hamada, Chizuko Toyoda, Genya Bokura, Hirokazu Yamaguchi, Shuhei Takahashi, Yukitoshi Neurol Int Case Report We report the case of a 64-year old man who presented memory disturbance, low-grade fever, weight loss, and bilateral hand tremors for three months. He was diagnosed with non-herpetic acute limbic encephalitis (NHALE). Follow-up magnetic resonance imaging (MRI) revealed new lesions after symptomatic improvement following steroid pulse therapy. This may indicate that there is a time lag between the disturbance or recovery of neurons and astrocytes. Thus, other lesions might occasionally appear during convalescence in patients with NHALE, even if only minimal lesions were found on the initial MRI. PAGEPress 2013-06-25 /pmc/articles/PMC3718248/ /pubmed/23888211 http://dx.doi.org/10.4081/ni.2013.e8 Text en ©Copyright N. Kohno et al.,
spellingShingle Case Report
Kohno, Naoto
Kawakami, Yuko
Hamada, Chizuko
Toyoda, Genya
Bokura, Hirokazu
Yamaguchi, Shuhei
Takahashi, Yukitoshi
A Discrepancy Between Clinical Course and Magnetic Resonance Imaging in a Case of Non-Herpetic Acute Limbic Encephalitis
title A Discrepancy Between Clinical Course and Magnetic Resonance Imaging in a Case of Non-Herpetic Acute Limbic Encephalitis
title_full A Discrepancy Between Clinical Course and Magnetic Resonance Imaging in a Case of Non-Herpetic Acute Limbic Encephalitis
title_fullStr A Discrepancy Between Clinical Course and Magnetic Resonance Imaging in a Case of Non-Herpetic Acute Limbic Encephalitis
title_full_unstemmed A Discrepancy Between Clinical Course and Magnetic Resonance Imaging in a Case of Non-Herpetic Acute Limbic Encephalitis
title_short A Discrepancy Between Clinical Course and Magnetic Resonance Imaging in a Case of Non-Herpetic Acute Limbic Encephalitis
title_sort discrepancy between clinical course and magnetic resonance imaging in a case of non-herpetic acute limbic encephalitis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718248/
https://www.ncbi.nlm.nih.gov/pubmed/23888211
http://dx.doi.org/10.4081/ni.2013.e8
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