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Neural crest cells are required for correct positioning of the developing outflow cushions and pattern the arterial valve leaflets

AIMS: Anomalies of the arterial valves, principally bicuspid aortic valve (BAV), are the most common congenital anomalies. The cellular mechanisms that underlie arterial valve development are poorly understood. While it is known that the valve leaflets derive from the outflow cushions, which are pop...

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Detalles Bibliográficos
Autores principales: Phillips, Helen M., Mahendran, Pavithra, Singh, Esha, Anderson, Robert H., Chaudhry, Bill, Henderson, Deborah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718324/
https://www.ncbi.nlm.nih.gov/pubmed/23723064
http://dx.doi.org/10.1093/cvr/cvt132