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Multiple roles of Activin/Nodal, bone morphogenetic protein, fibroblast growth factor and Wnt/β-catenin signalling in the anterior neural patterning of adherent human embryonic stem cell cultures

Several studies have successfully produced a variety of neural cell types from human embryonic stem cells (hESCs), but there has been limited systematic analysis of how different regional identities are established using well-defined differentiation conditions. We have used adherent, chemically defi...

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Detalles Bibliográficos
Autores principales: Lupo, Giuseppe, Novorol, Claire, Smith, Joseph R., Vallier, Ludovic, Miranda, Elena, Alexander, Morgan, Biagioni, Stefano, Pedersen, Roger A., Harris, William A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718331/
https://www.ncbi.nlm.nih.gov/pubmed/23576785
http://dx.doi.org/10.1098/rsob.120167