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Genetic diversity among Trypanosoma (Duttonella) vivax strains from Zambia and Ghana, based on cathepsin L-like gene
Understanding the evolutionary relationships of Trypanosoma (Duttonella) vivax genotypes between West Africa and Southern Africa can provide information on the epidemiology and control of trypanosomosis. Cattle blood samples from Zambia and Ghana were screened for T. vivax infection using specie-spe...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
EDP Sciences
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718526/ https://www.ncbi.nlm.nih.gov/pubmed/23815966 http://dx.doi.org/10.1051/parasite/2013024 |
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author | Nakayima, Jesca Nakao, Ryo Alhassan, Andy Hayashida, Kyoko Namangala, Boniface Mahama, Charles Afakye, Kofi Sugimoto, Chihiro |
author_facet | Nakayima, Jesca Nakao, Ryo Alhassan, Andy Hayashida, Kyoko Namangala, Boniface Mahama, Charles Afakye, Kofi Sugimoto, Chihiro |
author_sort | Nakayima, Jesca |
collection | PubMed |
description | Understanding the evolutionary relationships of Trypanosoma (Duttonella) vivax genotypes between West Africa and Southern Africa can provide information on the epidemiology and control of trypanosomosis. Cattle blood samples from Zambia and Ghana were screened for T. vivax infection using specie-specific PCR and sequencing analysis. Substantial polymorphism was obtained from phylogenetic analysis of sequences of cathepsin L-like catalytic domains. T. vivax from Ghana clustered together with West African and South American sequences, while T. vivax from Zambia formed one distinct clade and clustered with East African and Southern African sequences. This study suggests existence of distinct genetic diversity between T. vivax genotypes from West Africa and Zambia as per their geographical origins. |
format | Online Article Text |
id | pubmed-3718526 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | EDP Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-37185262013-07-24 Genetic diversity among Trypanosoma (Duttonella) vivax strains from Zambia and Ghana, based on cathepsin L-like gene Nakayima, Jesca Nakao, Ryo Alhassan, Andy Hayashida, Kyoko Namangala, Boniface Mahama, Charles Afakye, Kofi Sugimoto, Chihiro Parasite Research Article Understanding the evolutionary relationships of Trypanosoma (Duttonella) vivax genotypes between West Africa and Southern Africa can provide information on the epidemiology and control of trypanosomosis. Cattle blood samples from Zambia and Ghana were screened for T. vivax infection using specie-specific PCR and sequencing analysis. Substantial polymorphism was obtained from phylogenetic analysis of sequences of cathepsin L-like catalytic domains. T. vivax from Ghana clustered together with West African and South American sequences, while T. vivax from Zambia formed one distinct clade and clustered with East African and Southern African sequences. This study suggests existence of distinct genetic diversity between T. vivax genotypes from West Africa and Zambia as per their geographical origins. EDP Sciences 2013 2013-07-01 /pmc/articles/PMC3718526/ /pubmed/23815966 http://dx.doi.org/10.1051/parasite/2013024 Text en © J. Nakayima et al., published by EDP Sciences, 2013 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Nakayima, Jesca Nakao, Ryo Alhassan, Andy Hayashida, Kyoko Namangala, Boniface Mahama, Charles Afakye, Kofi Sugimoto, Chihiro Genetic diversity among Trypanosoma (Duttonella) vivax strains from Zambia and Ghana, based on cathepsin L-like gene |
title | Genetic diversity among Trypanosoma (Duttonella) vivax strains from Zambia and Ghana, based on cathepsin L-like gene |
title_full | Genetic diversity among Trypanosoma (Duttonella) vivax strains from Zambia and Ghana, based on cathepsin L-like gene |
title_fullStr | Genetic diversity among Trypanosoma (Duttonella) vivax strains from Zambia and Ghana, based on cathepsin L-like gene |
title_full_unstemmed | Genetic diversity among Trypanosoma (Duttonella) vivax strains from Zambia and Ghana, based on cathepsin L-like gene |
title_short | Genetic diversity among Trypanosoma (Duttonella) vivax strains from Zambia and Ghana, based on cathepsin L-like gene |
title_sort | genetic diversity among trypanosoma (duttonella) vivax strains from zambia and ghana, based on cathepsin l-like gene |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718526/ https://www.ncbi.nlm.nih.gov/pubmed/23815966 http://dx.doi.org/10.1051/parasite/2013024 |
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