Genetic diversity among Trypanosoma (Duttonella) vivax strains from Zambia and Ghana, based on cathepsin L-like gene

Understanding the evolutionary relationships of Trypanosoma (Duttonella) vivax genotypes between West Africa and Southern Africa can provide information on the epidemiology and control of trypanosomosis. Cattle blood samples from Zambia and Ghana were screened for T. vivax infection using specie-spe...

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Autores principales: Nakayima, Jesca, Nakao, Ryo, Alhassan, Andy, Hayashida, Kyoko, Namangala, Boniface, Mahama, Charles, Afakye, Kofi, Sugimoto, Chihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: EDP Sciences 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718526/
https://www.ncbi.nlm.nih.gov/pubmed/23815966
http://dx.doi.org/10.1051/parasite/2013024
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author Nakayima, Jesca
Nakao, Ryo
Alhassan, Andy
Hayashida, Kyoko
Namangala, Boniface
Mahama, Charles
Afakye, Kofi
Sugimoto, Chihiro
author_facet Nakayima, Jesca
Nakao, Ryo
Alhassan, Andy
Hayashida, Kyoko
Namangala, Boniface
Mahama, Charles
Afakye, Kofi
Sugimoto, Chihiro
author_sort Nakayima, Jesca
collection PubMed
description Understanding the evolutionary relationships of Trypanosoma (Duttonella) vivax genotypes between West Africa and Southern Africa can provide information on the epidemiology and control of trypanosomosis. Cattle blood samples from Zambia and Ghana were screened for T. vivax infection using specie-specific PCR and sequencing analysis. Substantial polymorphism was obtained from phylogenetic analysis of sequences of cathepsin L-like catalytic domains. T. vivax from Ghana clustered together with West African and South American sequences, while T. vivax from Zambia formed one distinct clade and clustered with East African and Southern African sequences. This study suggests existence of distinct genetic diversity between T. vivax genotypes from West Africa and Zambia as per their geographical origins.
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spelling pubmed-37185262013-07-24 Genetic diversity among Trypanosoma (Duttonella) vivax strains from Zambia and Ghana, based on cathepsin L-like gene Nakayima, Jesca Nakao, Ryo Alhassan, Andy Hayashida, Kyoko Namangala, Boniface Mahama, Charles Afakye, Kofi Sugimoto, Chihiro Parasite Research Article Understanding the evolutionary relationships of Trypanosoma (Duttonella) vivax genotypes between West Africa and Southern Africa can provide information on the epidemiology and control of trypanosomosis. Cattle blood samples from Zambia and Ghana were screened for T. vivax infection using specie-specific PCR and sequencing analysis. Substantial polymorphism was obtained from phylogenetic analysis of sequences of cathepsin L-like catalytic domains. T. vivax from Ghana clustered together with West African and South American sequences, while T. vivax from Zambia formed one distinct clade and clustered with East African and Southern African sequences. This study suggests existence of distinct genetic diversity between T. vivax genotypes from West Africa and Zambia as per their geographical origins. EDP Sciences 2013 2013-07-01 /pmc/articles/PMC3718526/ /pubmed/23815966 http://dx.doi.org/10.1051/parasite/2013024 Text en © J. Nakayima et al., published by EDP Sciences, 2013 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Nakayima, Jesca
Nakao, Ryo
Alhassan, Andy
Hayashida, Kyoko
Namangala, Boniface
Mahama, Charles
Afakye, Kofi
Sugimoto, Chihiro
Genetic diversity among Trypanosoma (Duttonella) vivax strains from Zambia and Ghana, based on cathepsin L-like gene
title Genetic diversity among Trypanosoma (Duttonella) vivax strains from Zambia and Ghana, based on cathepsin L-like gene
title_full Genetic diversity among Trypanosoma (Duttonella) vivax strains from Zambia and Ghana, based on cathepsin L-like gene
title_fullStr Genetic diversity among Trypanosoma (Duttonella) vivax strains from Zambia and Ghana, based on cathepsin L-like gene
title_full_unstemmed Genetic diversity among Trypanosoma (Duttonella) vivax strains from Zambia and Ghana, based on cathepsin L-like gene
title_short Genetic diversity among Trypanosoma (Duttonella) vivax strains from Zambia and Ghana, based on cathepsin L-like gene
title_sort genetic diversity among trypanosoma (duttonella) vivax strains from zambia and ghana, based on cathepsin l-like gene
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718526/
https://www.ncbi.nlm.nih.gov/pubmed/23815966
http://dx.doi.org/10.1051/parasite/2013024
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