First isolation and genetic characterization of a Toxoplasma gondii strain from a symptomatic human case of congenital toxoplasmosis in Romania

Very limited data exists on the genetic diversity of Toxoplasma gondii from Eastern Europe. We present the first Romanian case of symptomatic congenital toxoplasmosis in which the T. gondii strain was isolated after inoculation in mice of a cerebrospinal fluid sample from a living neonate. The T. go...

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Autores principales: Costache, Carmen Anca, Colosi, Horaţiu Alexandru, Blaga, Ligia, Györke, Adriana, Paştiu, Anamaria Ioana, Colosi, Ioana Alina, Ajzenberg, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: EDP Sciences 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718531/
https://www.ncbi.nlm.nih.gov/pubmed/23537840
http://dx.doi.org/10.1051/parasite/2013011
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author Costache, Carmen Anca
Colosi, Horaţiu Alexandru
Blaga, Ligia
Györke, Adriana
Paştiu, Anamaria Ioana
Colosi, Ioana Alina
Ajzenberg, Daniel
author_facet Costache, Carmen Anca
Colosi, Horaţiu Alexandru
Blaga, Ligia
Györke, Adriana
Paştiu, Anamaria Ioana
Colosi, Ioana Alina
Ajzenberg, Daniel
author_sort Costache, Carmen Anca
collection PubMed
description Very limited data exists on the genetic diversity of Toxoplasma gondii from Eastern Europe. We present the first Romanian case of symptomatic congenital toxoplasmosis in which the T. gondii strain was isolated after inoculation in mice of a cerebrospinal fluid sample from a living neonate. The T. gondii strain was genotyped with 15 microsatellite markers distributed on 10 of the 14 chromosomes of T. gondii. The strain had a type II genotype.
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spelling pubmed-37185312013-07-24 First isolation and genetic characterization of a Toxoplasma gondii strain from a symptomatic human case of congenital toxoplasmosis in Romania Costache, Carmen Anca Colosi, Horaţiu Alexandru Blaga, Ligia Györke, Adriana Paştiu, Anamaria Ioana Colosi, Ioana Alina Ajzenberg, Daniel Parasite Research Article Very limited data exists on the genetic diversity of Toxoplasma gondii from Eastern Europe. We present the first Romanian case of symptomatic congenital toxoplasmosis in which the T. gondii strain was isolated after inoculation in mice of a cerebrospinal fluid sample from a living neonate. The T. gondii strain was genotyped with 15 microsatellite markers distributed on 10 of the 14 chromosomes of T. gondii. The strain had a type II genotype. EDP Sciences 2013 2013-03-29 /pmc/articles/PMC3718531/ /pubmed/23537840 http://dx.doi.org/10.1051/parasite/2013011 Text en © C.A. Costache et al., published by EDP Sciences, 2013 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Costache, Carmen Anca
Colosi, Horaţiu Alexandru
Blaga, Ligia
Györke, Adriana
Paştiu, Anamaria Ioana
Colosi, Ioana Alina
Ajzenberg, Daniel
First isolation and genetic characterization of a Toxoplasma gondii strain from a symptomatic human case of congenital toxoplasmosis in Romania
title First isolation and genetic characterization of a Toxoplasma gondii strain from a symptomatic human case of congenital toxoplasmosis in Romania
title_full First isolation and genetic characterization of a Toxoplasma gondii strain from a symptomatic human case of congenital toxoplasmosis in Romania
title_fullStr First isolation and genetic characterization of a Toxoplasma gondii strain from a symptomatic human case of congenital toxoplasmosis in Romania
title_full_unstemmed First isolation and genetic characterization of a Toxoplasma gondii strain from a symptomatic human case of congenital toxoplasmosis in Romania
title_short First isolation and genetic characterization of a Toxoplasma gondii strain from a symptomatic human case of congenital toxoplasmosis in Romania
title_sort first isolation and genetic characterization of a toxoplasma gondii strain from a symptomatic human case of congenital toxoplasmosis in romania
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718531/
https://www.ncbi.nlm.nih.gov/pubmed/23537840
http://dx.doi.org/10.1051/parasite/2013011
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