Cargando…

Induction of apoptosis in melanoma A375 cells by a chloroform fraction of Centratherum anthelminticum (L.) seeds involves NF-kappaB, p53 and Bcl-2-controlled mitochondrial signaling pathways

BACKGROUND: Centratherum anthelminticum (L.) Kuntze (scientific synonyms: Vernonia anthelmintica; black cumin) is one of the ingredients of an Ayurvedic preparation, called “Kayakalp”, commonly applied to treat skin disorders in India and Southeast Asia. Despite its well known anti-inflammatory prop...

Descripción completa

Detalles Bibliográficos
Autores principales:	Looi, Chung Yeng, Moharram, Bushra, Paydar, Mohammadjavad, Wong, Yi Li, Leong, Kok Hoong, Mohamad, Khalit, Arya, Aditya, Wong, Won Fen, Mustafa, Mohd Rais
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718627/ https://www.ncbi.nlm.nih.gov/pubmed/23837445 http://dx.doi.org/10.1186/1472-6882-13-166

Ejemplares similares

Induction of Apoptosis in Human Breast Cancer Cells via Caspase Pathway by Vernodalin Isolated from Centratherum anthelminticum (L.) Seeds
por: Looi, Chung Yeng, et al.
Publicado: (2013)

Evaluation of Antiinflammatory Activity of Centratherum anthelminticum (L) Kuntze Seed
por: Ashok, Purnima, et al.
Publicado: (2010)

Chloroform Fraction of Centratherum anthelminticum (L.) Seed Inhibits Tumor Necrosis Factor Alpha and Exhibits Pleotropic Bioactivities: Inhibitory Role in Human Tumor Cells
por: Arya, Aditya, et al.
Publicado: (2012)

Evaluation of Analgesic and Antipyretic Activities of Centratherum anthelminticum (L) Kuntze Seed
por: Purnima, A., et al.
Publicado: (2009)

Antioxidant potential of bitter cumin (Centratherum anthelminticum (L.) Kuntze) seeds in in vitro models
por: Ani, V, et al.
Publicado: (2011)

Chemical Characterization and Ameliorating Effect of Centratherum anthelminticum Extract against Polycystic Ovary Syndrome in Wistar Rats
por: Shoaib, Moonis, et al.
Publicado: (2023)

In vitro antifungal activity of different components of Centratherum anthelminticum and Ocimum sanctum seed oils and their synergism against oral pathogenic fungi
por: H Gopalkrishna, Aparna, et al.
Publicado: (2016)

NF-kappaB in Lung Tumorigenesis
por: Cai, Zhenjian, et al.
Publicado: (2011)

Chenopodium Anthelminticum
por: Maclay, C. B.
Publicado: (1887)

Evaluation of cytotoxic and chemotherapeutic properties of boldine in breast cancer using in vitro and in vivo models
por: Paydar, Mohammadjavad, et al.
Publicado: (2014)

Antioxidant and anti-inflammatory activities of Centratherum anthelminticum (L.) Kuntze seed oil in diabetic nephropathy via modulation of Nrf-2/HO-1 and NF-κB pathway
por: Baig, Nida, et al.
Publicado: (2022)

Persea declinata (Bl.) Kosterm Bark Crude Extract Induces Apoptosis in MCF-7 Cells via G(0)/G(1) Cell Cycle Arrest, Bcl-2/Bax/Bcl-xl Signaling Pathways, and ROS Generation
por: Narrima, Putri, et al.
Publicado: (2014)

Antidiabetic and Antioxidant Properties of Alkaloids from Catharanthus roseus (L.) G. Don
por: Tiong, Soon Huat, et al.
Publicado: (2013)

Nuclear factor kappaB (NF-kappaB) pathway as a therapeutic target in rheumatoid arthritis.
por: Jue, D. M., et al.
Publicado: (1999)

Subditine, a New Monoterpenoid Indole Alkaloid from Bark of Nauclea subdita (Korth.) Steud. Induces Apoptosis in Human Prostate Cancer Cells
por: Liew, Sook Yee, et al.
Publicado: (2014)

Bcl-2 down-regulates the activity of transcription factor NF-kappaB induced upon apoptosis
Publicado: (1996)

NF-kappaB and cytokines in pancreatic acinar cells.
por: Kim, H, et al.
Publicado: (2000)

Nuclear Factor-kappaB in Autoimmunity: Man and Mouse
por: Miraghazadeh, Bahar, et al.
Publicado: (2018)

NF-kappaB: Two Sides of the Same Coin
por: Pires, Bruno R. B., et al.
Publicado: (2018)

An Update on the Multifaceted Role of NF-kappaB in Endometriosis
por: Liu, Yuanmeng, et al.
Publicado: (2022)

Prevalence, antimicrobial susceptibility and virulotyping of Listeria species and Listeria monocytogenes isolated from open-air fish markets
por: Jamali, Hossein, et al.
Publicado: (2015)

Recent insights into the role of NF-kappaB in ovarian carcinogenesis
por: Alvero, Ayesha B
Publicado: (2010)

NF-kappaB Signaling in Chronic Inflammatory Airway Disease
por: Schuliga, Michael
Publicado: (2015)

Dentatin Induces Apoptosis in Prostate Cancer Cells via Bcl-2, Bcl-xL, Survivin Downregulation, Caspase-9, -3/7 Activation, and NF-κB Inhibition
por: Arbab, Ismail Adam, et al.
Publicado: (2012)

Interplay of Murine Gammaherpesvirus 68 with NF-kappaB Signaling of the Host
por: Cieniewicz, Brandon, et al.
Publicado: (2016)

NF-kappaB Regulates Redox Status in Breast Cancer Subtypes
por: Pires, Bruno R. B., et al.
Publicado: (2018)

Ancestral function of Inhibitors-of-kappaB regulates Caenorhabditis elegans development
por: Brena, David, et al.
Publicado: (2020)

Panduratin A Inhibits the Growth of A549 Cells through Induction of Apoptosis and Inhibition of NF-KappaB Translocation
por: Cheah, Shiau-Chuen, et al.
Publicado: (2011)

Modulation of LPS stimulated NF-kappaB mediated Nitric Oxide production by PKCε and JAK2 in RAW macrophages
por: Jones, Edward, et al.
Publicado: (2007)

Sensitization of ovarian cancer cells to cisplatin by genistein: the role of NF-kappaB
por: Solomon, Leigh A, et al.
Publicado: (2008)

In silico identification of NF-kappaB-regulated genes in pancreatic beta-cells
por: Naamane, Najib, et al.
Publicado: (2007)

Expression of NF-kappaB and cytokines in chronic rejection of transplanted murine heart.
por: Lee, J. R., et al.
Publicado: (2001)

NF-kappaB Mediated Transcriptional Repression of Acid Modifying Hormone Gastrin
por: Datta De, Dipanjana, et al.
Publicado: (2013)

NF-kappaB Signaling Pathways in Neurological Inflammation: A Mini Review
por: Shih, Ruey-Horng, et al.
Publicado: (2015)

NF-kappaB Is Involved in the Regulation of EMT Genes in Breast Cancer Cells
por: Pires, Bruno R. B., et al.
Publicado: (2017)

Piperlongumine Improves Lipopolysaccharide-Induced Amyloidogenesis by Suppressing NF-KappaB Pathway
por: Gu, Sun Mi, et al.
Publicado: (2018)

Cell-Type Targeted NF-kappaB Inhibition for the Treatment of Inflammatory Diseases
por: Sehnert, Bettina, et al.
Publicado: (2020)

Dihydromyricetin Attenuates Inflammation through TLR4/NF-kappaB Pathway
por: Jing, Nianshui, et al.
Publicado: (2019)

E3 ubiquitin ligase tripartite motif-containing 71 promotes the proliferation of non-small cell lung cancer through the inhibitor of kappaB-α/nuclear factor kappaB pathway
por: Ren, Hongjiu, et al.
Publicado: (2017)

RTKN2 Induces NF-KappaB Dependent Resistance to Intrinsic Apoptosis in HEK Cells and Regulates BCL-2 Genes in Human CD4(+) Lymphocytes
por: Collier, Fiona M, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_6nsaeefpaiqd21n2tmu7br5sm8