Fibrinogen Aα Thr312Ala Polymorphism Specifically Contributes to Chronic Thromboembolic Pulmonary Hypertension by Increasing Fibrin Resistance

BACKGROUND: Polymorphisms are associated with chronic thromboembolic pulmonary hypertension (CTEPH) and pulmonary thromboembolism (PTE), but no polymorphism specific to CTEPH but not PTE has yet been reported. Fibrin resistance is associated with CTEPH, but the mechanism has not been elucidated. MET...

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Detalles Bibliográficos
Autores principales: Li, Ji-Feng, Lin, Yuan, Yang, Yuan-Hua, Gan, Hui-Li, Liang, Yan, Liu, Jie, Yang, Su-Qiao, Zhang, Wei-Juan, Cui, Na, Zhao, Lan, Zhai, Zhen-Guo, Wang, Jun, Wang, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718692/
https://www.ncbi.nlm.nih.gov/pubmed/23894515
http://dx.doi.org/10.1371/journal.pone.0069635

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