Ablation of astrocytic laminin impairs vascular smooth muscle cell function and leads to hemorrhagic stroke

Astrocytes express laminin and assemble basement membranes (BMs) at their endfeet, which ensheath the cerebrovasculature. The function of astrocytic laminin in cerebrovascular integrity is unknown. We show that ablation of astrocytic laminin by tissue-specific Cre-mediated recombination disrupted en...

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Detalles Bibliográficos
Autores principales: Chen, Zu-Lin, Yao, Yao, Norris, Erin H., Kruyer, Anna, Jno-Charles, Odella, Akhmerov, Akbarshakh, Strickland, Sidney
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718965/
https://www.ncbi.nlm.nih.gov/pubmed/23857767
http://dx.doi.org/10.1083/jcb.201212032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718965/
https://www.ncbi.nlm.nih.gov/pubmed/23857767
http://dx.doi.org/10.1083/jcb.201212032

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