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Ablation of astrocytic laminin impairs vascular smooth muscle cell function and leads to hemorrhagic stroke
Astrocytes express laminin and assemble basement membranes (BMs) at their endfeet, which ensheath the cerebrovasculature. The function of astrocytic laminin in cerebrovascular integrity is unknown. We show that ablation of astrocytic laminin by tissue-specific Cre-mediated recombination disrupted en...
Autores principales: | Chen, Zu-Lin, Yao, Yao, Norris, Erin H., Kruyer, Anna, Jno-Charles, Odella, Akhmerov, Akbarshakh, Strickland, Sidney |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718965/ https://www.ncbi.nlm.nih.gov/pubmed/23857767 http://dx.doi.org/10.1083/jcb.201212032 |
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