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Kinesin-5/Eg5 is important for transport of CARTS from the trans-Golgi network to the cell surface

Here we report that the kinesin-5 motor Klp61F, which is known for its role in bipolar spindle formation in mitosis, is required for protein transport from the Golgi complex to the cell surface in Drosophila S2 cells. Disrupting the function of its mammalian orthologue, Eg5, in HeLa cells inhibited...

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Detalles Bibliográficos
Autores principales:	Wakana, Yuichi, Villeneuve, Julien, van Galen, Josse, Cruz-Garcia, David, Tagaya, Mitsuo, Malhotra, Vivek
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2013
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718972/ https://www.ncbi.nlm.nih.gov/pubmed/23857769 http://dx.doi.org/10.1083/jcb.201303163

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