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Kinesin-5/Eg5 is important for transport of CARTS from the trans-Golgi network to the cell surface
Here we report that the kinesin-5 motor Klp61F, which is known for its role in bipolar spindle formation in mitosis, is required for protein transport from the Golgi complex to the cell surface in Drosophila S2 cells. Disrupting the function of its mammalian orthologue, Eg5, in HeLa cells inhibited...
Autores principales: | Wakana, Yuichi, Villeneuve, Julien, van Galen, Josse, Cruz-Garcia, David, Tagaya, Mitsuo, Malhotra, Vivek |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718972/ https://www.ncbi.nlm.nih.gov/pubmed/23857769 http://dx.doi.org/10.1083/jcb.201303163 |
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