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The association of serum prolidase activity with developmental dysplasia of the hip
The purpose of this study was to evaluate serum prolidase activity in patients with developmental dysplasia of the hip (DDH). Prolidase enzyme activity was measured spectrophotometrically to pointing out the collagen metabolism. The prolidase activity in patients with DDH was significantly higher th...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718991/ https://www.ncbi.nlm.nih.gov/pubmed/23338227 http://dx.doi.org/10.1007/s00296-013-2672-9 |
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author | Soran, N. Altindag, O. Aksoy, N. Çakır, H. Taşkın, A. Soran, M. Işıkan, E. |
author_facet | Soran, N. Altindag, O. Aksoy, N. Çakır, H. Taşkın, A. Soran, M. Işıkan, E. |
author_sort | Soran, N. |
collection | PubMed |
description | The purpose of this study was to evaluate serum prolidase activity in patients with developmental dysplasia of the hip (DDH). Prolidase enzyme activity was measured spectrophotometrically to pointing out the collagen metabolism. The prolidase activity in patients with DDH was significantly higher than that in the control group (p = 0.002). Furthermore, there was positive correlation between prolidase activity and dysplasia level. Increased serum prolidase activity may have played a role in the presence of DDH. We therefore hypothesized that the increased prolidase activity related to collagen turnover may be associated with etiopathogenesis and/or the progression of the disease. |
format | Online Article Text |
id | pubmed-3718991 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-37189912013-07-24 The association of serum prolidase activity with developmental dysplasia of the hip Soran, N. Altindag, O. Aksoy, N. Çakır, H. Taşkın, A. Soran, M. Işıkan, E. Rheumatol Int Original Article The purpose of this study was to evaluate serum prolidase activity in patients with developmental dysplasia of the hip (DDH). Prolidase enzyme activity was measured spectrophotometrically to pointing out the collagen metabolism. The prolidase activity in patients with DDH was significantly higher than that in the control group (p = 0.002). Furthermore, there was positive correlation between prolidase activity and dysplasia level. Increased serum prolidase activity may have played a role in the presence of DDH. We therefore hypothesized that the increased prolidase activity related to collagen turnover may be associated with etiopathogenesis and/or the progression of the disease. Springer Berlin Heidelberg 2013-01-22 2013 /pmc/articles/PMC3718991/ /pubmed/23338227 http://dx.doi.org/10.1007/s00296-013-2672-9 Text en © The Author(s) 2013 https://creativecommons.org/licenses/by/2.0/ Open AccessThis article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited. |
spellingShingle | Original Article Soran, N. Altindag, O. Aksoy, N. Çakır, H. Taşkın, A. Soran, M. Işıkan, E. The association of serum prolidase activity with developmental dysplasia of the hip |
title | The association of serum prolidase activity with developmental dysplasia of the hip |
title_full | The association of serum prolidase activity with developmental dysplasia of the hip |
title_fullStr | The association of serum prolidase activity with developmental dysplasia of the hip |
title_full_unstemmed | The association of serum prolidase activity with developmental dysplasia of the hip |
title_short | The association of serum prolidase activity with developmental dysplasia of the hip |
title_sort | association of serum prolidase activity with developmental dysplasia of the hip |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718991/ https://www.ncbi.nlm.nih.gov/pubmed/23338227 http://dx.doi.org/10.1007/s00296-013-2672-9 |
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