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Listerin-Dependent Nascent Protein Ubiquitination Relies on Ribosome Subunit Dissociation
Quality control of defective mRNAs relies on their translation to detect the lesion. Aberrant proteins are therefore an obligate byproduct of mRNA surveillance and must be degraded to avoid disrupting protein homeostasis. These defective translation products are thought to be ubiquitinated at the ri...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3719020/ https://www.ncbi.nlm.nih.gov/pubmed/23685075 http://dx.doi.org/10.1016/j.molcel.2013.04.015 |