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Diagnostic accuracy of preoperative tests for lymph node status in endometrial cancer: a systematic review
Background: Approximately 72% of endometrial cancers are FIGO stage I at diagnosis and about 10% have lymph node metastases. An ideal diagnostic test for nodal disease would be able to prevent both overtreatment (i.e. unnecessary lymphadenectomy) and undertreatment (i.e. withholding lymphadenectomy...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
e-Med
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3719052/ https://www.ncbi.nlm.nih.gov/pubmed/23876490 http://dx.doi.org/10.1102/1470-7330.2013.0032 |
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author | Pelikan, H.M.P. Trum, J.W. Bakers, F.C.H. Beets-Tan, R.G.H. Smits, L.J.M. Kruitwagen, R.F.P.M. |
author_facet | Pelikan, H.M.P. Trum, J.W. Bakers, F.C.H. Beets-Tan, R.G.H. Smits, L.J.M. Kruitwagen, R.F.P.M. |
author_sort | Pelikan, H.M.P. |
collection | PubMed |
description | Background: Approximately 72% of endometrial cancers are FIGO stage I at diagnosis and about 10% have lymph node metastases. An ideal diagnostic test for nodal disease would be able to prevent both overtreatment (i.e. unnecessary lymphadenectomy) and undertreatment (i.e. withholding lymphadenectomy or adjuvant postoperative treatment to patients with lymph node metastases). Objectives: In this review we compare the accuracy of preoperative tests (computed tomography, magnetic resonance imaging, positron emission tomography-computed tomography, CA-125 serum levels, and ultrasonography) for the detection of lymph node metastases in endometrial cancers with the final histopathologic diagnosis after complete pelvic and para-aortic lymphadenectomy as the gold standard. Method: A systematic search in MEDLINE (using PubMed), Embase and The Cochrane Library was performed up to 23 July 2012. Results: We found one article that met our inclusion criteria for computed tomography, none for magnetic resonance imaging, 2 for positron emission tomography/computed tomography), 2 for CA-125 and none for ultrasonography. Conclusions: Due to the lack of high-quality articles on a preoperative test for lymph node status in endometrial cancer, no proper comparison between these modalities can be made. |
format | Online Article Text |
id | pubmed-3719052 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | e-Med |
record_format | MEDLINE/PubMed |
spelling | pubmed-37190522014-06-13 Diagnostic accuracy of preoperative tests for lymph node status in endometrial cancer: a systematic review Pelikan, H.M.P. Trum, J.W. Bakers, F.C.H. Beets-Tan, R.G.H. Smits, L.J.M. Kruitwagen, R.F.P.M. Cancer Imaging Review Background: Approximately 72% of endometrial cancers are FIGO stage I at diagnosis and about 10% have lymph node metastases. An ideal diagnostic test for nodal disease would be able to prevent both overtreatment (i.e. unnecessary lymphadenectomy) and undertreatment (i.e. withholding lymphadenectomy or adjuvant postoperative treatment to patients with lymph node metastases). Objectives: In this review we compare the accuracy of preoperative tests (computed tomography, magnetic resonance imaging, positron emission tomography-computed tomography, CA-125 serum levels, and ultrasonography) for the detection of lymph node metastases in endometrial cancers with the final histopathologic diagnosis after complete pelvic and para-aortic lymphadenectomy as the gold standard. Method: A systematic search in MEDLINE (using PubMed), Embase and The Cochrane Library was performed up to 23 July 2012. Results: We found one article that met our inclusion criteria for computed tomography, none for magnetic resonance imaging, 2 for positron emission tomography/computed tomography), 2 for CA-125 and none for ultrasonography. Conclusions: Due to the lack of high-quality articles on a preoperative test for lymph node status in endometrial cancer, no proper comparison between these modalities can be made. e-Med 2013-07-22 /pmc/articles/PMC3719052/ /pubmed/23876490 http://dx.doi.org/10.1102/1470-7330.2013.0032 Text en © 2013 International Cancer Imaging Society |
spellingShingle | Review Pelikan, H.M.P. Trum, J.W. Bakers, F.C.H. Beets-Tan, R.G.H. Smits, L.J.M. Kruitwagen, R.F.P.M. Diagnostic accuracy of preoperative tests for lymph node status in endometrial cancer: a systematic review |
title | Diagnostic accuracy of preoperative tests for lymph node status in endometrial cancer: a systematic review |
title_full | Diagnostic accuracy of preoperative tests for lymph node status in endometrial cancer: a systematic review |
title_fullStr | Diagnostic accuracy of preoperative tests for lymph node status in endometrial cancer: a systematic review |
title_full_unstemmed | Diagnostic accuracy of preoperative tests for lymph node status in endometrial cancer: a systematic review |
title_short | Diagnostic accuracy of preoperative tests for lymph node status in endometrial cancer: a systematic review |
title_sort | diagnostic accuracy of preoperative tests for lymph node status in endometrial cancer: a systematic review |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3719052/ https://www.ncbi.nlm.nih.gov/pubmed/23876490 http://dx.doi.org/10.1102/1470-7330.2013.0032 |
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