Repression of Factor VIII Inhibitor Development with Apoptotic Factor VIII-expressing Embryonic Stem Cells

Development of factor VIII (fVIII)-neutralizing antibodies, called inhibitors, is a challenging problem in the management of hemophilia A patients. We explored the possibility of pretreatment with apoptotic fVIII-expressing embryonic stem (ES) cells to prevent the development of fVIII inhibitors. Mu...

Descripción completa

Detalles Bibliográficos
Autores principales: Sakurai, Yoshihiko, Kasuda, Shogo, Tatsumi, Kohei, Takeda, Tomohiro, Kato, Junko, Kubo, Atsushi, Shima, Midori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3719103/
https://www.ncbi.nlm.nih.gov/pubmed/23888245
http://dx.doi.org/10.4081/hr.2013.e9

Ejemplares similares

Ejemplares similares