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Molecular Dynamics of Rab7::REP1::GGTase-II Ternary Complex and Identification of Their Putative Drug Binding Sites

The structure-function correlation of membrane proteins have been a difficult task, particularly in context to transient protein complexes. The molecular simulation of ternary complex of Rab7::REP1::GGTase-II was carried out to understand the basic structural events occurring during the prenylation...

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Detalles Bibliográficos
Autores principales: Sindhu, Meenakshi, Saini, Vandana, Piplani, Sakshi, Kumar, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3719145/
https://www.ncbi.nlm.nih.gov/pubmed/23901157
http://dx.doi.org/10.4103/0250-474X.113534