An exceptional case of myelodysplastic syndrome with myelofibrosis following combination chemotherapy for squamous cell lung cancer

A 60-year-old woman with squamous cell carcinoma in the right lung was successfully treated with four cycles of combination chemotherapy after surgery, and complete remission was achieved. However, the patient developed myelodysplastic syndrome (MDS) RAEB-2 with myelofibrosis after remission, possib...

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Detalles Bibliográficos
Autores principales: Wang, Yi-Hao, Fu, Rong, Shao, Zong-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Anti-Cancer Association 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3719187/
https://www.ncbi.nlm.nih.gov/pubmed/23882429
http://dx.doi.org/10.7497/j.issn.2095-3941.2013.02.010
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author Wang, Yi-Hao
Fu, Rong
Shao, Zong-Hong
author_facet Wang, Yi-Hao
Fu, Rong
Shao, Zong-Hong
author_sort Wang, Yi-Hao
collection PubMed
description A 60-year-old woman with squamous cell carcinoma in the right lung was successfully treated with four cycles of combination chemotherapy after surgery, and complete remission was achieved. However, the patient developed myelodysplastic syndrome (MDS) RAEB-2 with myelofibrosis after remission, possibly because of chemotherapy or DNA methylation. The patient responded well to dacitabine (Dacogen), suggesting that DNA hypomethylation agents can be a promising therapy to retard the progression of a second tumor or carcinoma.
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spelling pubmed-37191872013-07-23 An exceptional case of myelodysplastic syndrome with myelofibrosis following combination chemotherapy for squamous cell lung cancer Wang, Yi-Hao Fu, Rong Shao, Zong-Hong Cancer Biol Med Case Report A 60-year-old woman with squamous cell carcinoma in the right lung was successfully treated with four cycles of combination chemotherapy after surgery, and complete remission was achieved. However, the patient developed myelodysplastic syndrome (MDS) RAEB-2 with myelofibrosis after remission, possibly because of chemotherapy or DNA methylation. The patient responded well to dacitabine (Dacogen), suggesting that DNA hypomethylation agents can be a promising therapy to retard the progression of a second tumor or carcinoma. Chinese Anti-Cancer Association 2013-06 /pmc/articles/PMC3719187/ /pubmed/23882429 http://dx.doi.org/10.7497/j.issn.2095-3941.2013.02.010 Text en 2013 Cancer Biology & Medicine This work is licensed under a Creative Commons Attribution 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by/3.0/
spellingShingle Case Report
Wang, Yi-Hao
Fu, Rong
Shao, Zong-Hong
An exceptional case of myelodysplastic syndrome with myelofibrosis following combination chemotherapy for squamous cell lung cancer
title An exceptional case of myelodysplastic syndrome with myelofibrosis following combination chemotherapy for squamous cell lung cancer
title_full An exceptional case of myelodysplastic syndrome with myelofibrosis following combination chemotherapy for squamous cell lung cancer
title_fullStr An exceptional case of myelodysplastic syndrome with myelofibrosis following combination chemotherapy for squamous cell lung cancer
title_full_unstemmed An exceptional case of myelodysplastic syndrome with myelofibrosis following combination chemotherapy for squamous cell lung cancer
title_short An exceptional case of myelodysplastic syndrome with myelofibrosis following combination chemotherapy for squamous cell lung cancer
title_sort exceptional case of myelodysplastic syndrome with myelofibrosis following combination chemotherapy for squamous cell lung cancer
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3719187/
https://www.ncbi.nlm.nih.gov/pubmed/23882429
http://dx.doi.org/10.7497/j.issn.2095-3941.2013.02.010
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