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Allosteric Communication in the KIX Domain Proceeds through Dynamic Repacking of the Hydrophobic Core
[Image: see text] The KIX domain of the transcriptional coactivator CREB binding protein (CBP) co-operatively mediates interactions between transcription factors. Binding of the transcription factor mixed-lineage leukemia (MLL) induces the formation of a low-populated conformer of KIX that resembles...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical Society
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3719477/ https://www.ncbi.nlm.nih.gov/pubmed/23651431 http://dx.doi.org/10.1021/cb4002188 |