Cargando…

Cell Type-Specific Dependency on the PI3K/Akt Signaling Pathway for the Endogenous Epo and VEGF Induction by Baicalein in Neurons versus Astrocytes

The neuroprotective effect of baicalein is generally attributed to inhibition of 12/15-lipoxygenase (12/15-LOX) and suppression of oxidative stress, but recent studies showed that baicalein also activates hypoxia-inducible factor-α (HIF1α) through inhibition of prolyl hydrolase 2 (PHD2) and activati...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sun, Yu-Yo, Lin, Shang-Hsuan, Lin, Hung-Cheng, Hung, Chia-Chi, Wang, Chen-Yu, Lin, Yen-Chu, Hung, Kuo-Sheng, Lien, Cheng-Chang, Kuan, Chia-Yi, Lee, Yi-Hsuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3719842/ https://www.ncbi.nlm.nih.gov/pubmed/23904909 http://dx.doi.org/10.1371/journal.pone.0069019

Ejemplares similares

Curcumin Facilitates Aryl Hydrocarbon Receptor Activation to Ameliorate Inflammatory Astrogliosis
por: Lin, Chun-Hua, et al.
Publicado: (2022)

Baicalein protects against oxLDL-caused oxidative stress and inflammation by modulation of AMPK- alpha
por: Tsai, Kun-Ling, et al.
Publicado: (2016)

Development of a nested PCR assay for detecting Colletotrichum siamense and Colletotrichum fructicola on symptomless strawberry plants
por: Chung, Pei-Che, et al.
Publicado: (2022)

Inhibition of VEGF(165)/VEGFR2-dependent signaling by LECT2 suppresses hepatocellular carcinoma angiogenesis
por: Chen, Chi-Kuan, et al.
Publicado: (2016)

Active Tumor Permeation and Uptake of Surface Charge-Switchable Theranostic Nanoparticles for Imaging-Guided Photothermal/Chemo Combinatorial Therapy
por: Hung, Chia-Chian, et al.
Publicado: (2016)

Active Tumor Permeation and Uptake of Surface Charge-Switchable Theranostic Nanoparticles for Imaging-Guided Photothermal/Chemo Combinatorial Therapy: Erratum
por: Hung, Chia-Chian, et al.
Publicado: (2017)

A Commonly Used Chinese Herbal Formula, Shu-Jing-Hwo-Shiee-Tang, Potentiates Anticoagulant Activity of Warfarin in a Rabbit Model
por: Yang, Sien-Hung, et al.
Publicado: (2013)

Subtoxic Levels of Apigenin Inhibit Expression and Secretion of VEGF by Uveal Melanoma Cells via Suppression of ERK1/2 and PI3K/Akt Pathways
por: Chao, Shih-Chun, et al.
Publicado: (2013)

Baicalein is an available anti-atherosclerotic compound through modulation of nitric oxide-related mechanism under oxLDL exposure
por: Chan, Shih-Hung, et al.
Publicado: (2016)

Renal and Glucose-Lowering Effects of Empagliflozin and Dapagliflozin in Different Chronic Kidney Disease Stages
por: Lin, Yi-Hsuan, et al.
Publicado: (2019)

A Genetic Analysis of Taoyuan Pig and Its Phylogenetic Relationship to Eurasian Pig Breeds
por: Li, Kuan-Yi, et al.
Publicado: (2015)

Baicalein, 7,8-Dihydroxyflavone and Myricetin as Potent Inhibitors of Human Ornithine Decarboxylase
por: Liu, Yun-Chin, et al.
Publicado: (2020)

Detection of aqueous VEGF concentrations before and after intravitreal injection of anti-VEGF antibody using low-volume sampling paper-based ELISA
por: Hsu, Min-Yen, et al.
Publicado: (2016)

Vasculoprotective Potential of Baicalein in Angiotensin II-Infused Abdominal Aortic Aneurysms through Inhibiting Inflammation and Oxidative Stress
por: Sulistyowati, Erna, et al.
Publicado: (2023)

LDOC1 Suppresses Microbe-Induced Production of IL-1β in Human Normal and Cancerous Oral Cells through the PI3K/Akt/GSK-3β Axis
por: Lee, Chia-Huei, et al.
Publicado: (2020)

Dietary delphinidin inhibits human colorectal cancer metastasis associating with upregulation of miR-204-3p and suppression of the integrin/FAK axis
por: Huang, Chi-Chou, et al.
Publicado: (2019)

Targeting the conserved coronavirus octamer motif GGAAGAGC is a strategy for the development of coronavirus vaccine
por: Lin, Ching-Hung, et al.
Publicado: (2023)

Impact of Carbohydrate on Glucose Variability in Patients with Type 1 Diabetes Assessed Through Professional Continuous Glucose Monitoring: A Retrospective Study
por: Lin, Yi-Hsuan, et al.
Publicado: (2019)

Radiation-induced VEGF-C expression and endothelial cell proliferation in lung cancer
por: Chen, Yu-Hsuan, et al.
Publicado: (2014)

Optimal Lymph Node Yield for Survival Prediction in Rectal Cancer Patients After Neoadjuvant Therapy
por: Lin, Yu-Min, et al.
Publicado: (2021)

Discovery of 5,7-Dimethoxy-2-(3,4,5-trimethoxyphenoxy)-chromen-4-one with Lipid Lowering Effects in Hepatocytes
por: Chang, Yi-Han, et al.
Publicado: (2022)

Increased risk of keratopathy after psoriasis: A nationwide population-based study
por: Lee, Chia-Yi, et al.
Publicado: (2018)

Coadministration of DPP-4 inhibitor and insulin therapy does not further reduce the risk of cardiovascular events compared with DPP-4 inhibitor therapy in diabetic foot patients: a nationwide population-based study
por: Lin, Yi-Hsuan, et al.
Publicado: (2018)

Regimen comprising GLP-1 receptor agonist and basal insulin can decrease the effect of food on glycemic variability compared to a pre-mixed insulin regimen
por: Lin, Yi-Hsuan, et al.
Publicado: (2022)

Camphorataimide B suppresses the metastasis of human colorectal cancer cell by inhibiting Smad/FAK/Akt axis and promoting degradation of Snail/BMP4 complex
por: Huang, Chi-Chou, et al.
Publicado: (2022)

AKT/mTOR as Novel Targets of Polyphenol Piceatannol Possibly Contributing to Inhibition of Proliferation of Cultured Prostate Cancer Cells
por: Hsieh, Tze-Chen, et al.
Publicado: (2012)

Cancer cells increase endothelial cell tube formation and survival by activating the PI3K/Akt signalling pathway
por: Cheng, Hao-Wei, et al.
Publicado: (2017)

Baicalein induces apoptosis in esophageal squamous cell carcinoma cells through modulation of the PI3K/Akt pathway
por: ZHANG, HONG-BO, et al.
Publicado: (2013)

Baseline Cerebro-Cerebellar Functional Connectivity in Afferent and Efferent Pathways Reveal Dissociable Improvements in Visuomotor Learning
por: Lin, Yi-Cheng, et al.
Publicado: (2022)

Aging‐induced Akt activation involves in aging‐related pathologies and Aβ‐induced toxicity
por: Chen, Yu‐Ru, et al.
Publicado: (2019)

Association Between Chronic Osteomyelitis and Risk of End-Stage Renal Disease: A Nationwide Population-Based Cohort Study
por: Lin, Shih-Yi, et al.
Publicado: (2015)

Risk of Migraine in Patients With Asthma: A Nationwide Cohort Study
por: Peng, Yi-Hao, et al.
Publicado: (2016)

Association of Tramadol and Hypoglycemia in Diabetic Asians
por: Li, Shang-Yi, et al.
Publicado: (2018)

The Different Cardiovascular Outcomes Between Long-Term Efficacy of Hydrophilic and Lipophilic Statin Therapy in Both Asian Diabetic Sexes
por: Li, Shang-Yi, et al.
Publicado: (2019)

VEGF expression correlates with neuronal differentiation and predicts a favorable prognosis in patients with neuroblastoma
por: Weng, Wen-Chin, et al.
Publicado: (2017)

Adversarial Patch Attacks on Deep-Learning-Based Face Recognition Systems Using Generative Adversarial Networks
por: Hwang, Ren-Hung, et al.
Publicado: (2023)

Bimanual coordination deficits in hands following stroke and their relationship with motor and functional performance
por: Lai, Chien-Hung, et al.
Publicado: (2019)

Association Between Low Serum Testosterone and the Development of Metabolic Syndrome in Elderly Taiwanese Men
por: Zhong, Shang-Rong, et al.
Publicado: (2021)

Comparison of Clinical Outcomes of Radical Prostatectomy versus IMRT with Long-Term Hormone Therapy for Relatively Young Patients with High- to Very High-Risk Localized Prostate Cancer
por: Shih, Hung-Jen, et al.
Publicado: (2021)

Asialo-rhuEPO as a Potential Neuroprotectant for Ischemic Stroke Treatment
por: Kittur, Farooqahmed S., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_60alpqa9mhsmrg2fv83oi1p7gi