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Cell Type-Specific Dependency on the PI3K/Akt Signaling Pathway for the Endogenous Epo and VEGF Induction by Baicalein in Neurons versus Astrocytes

The neuroprotective effect of baicalein is generally attributed to inhibition of 12/15-lipoxygenase (12/15-LOX) and suppression of oxidative stress, but recent studies showed that baicalein also activates hypoxia-inducible factor-α (HIF1α) through inhibition of prolyl hydrolase 2 (PHD2) and activati...

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Detalles Bibliográficos
Autores principales:	Sun, Yu-Yo, Lin, Shang-Hsuan, Lin, Hung-Cheng, Hung, Chia-Chi, Wang, Chen-Yu, Lin, Yen-Chu, Hung, Kuo-Sheng, Lien, Cheng-Chang, Kuan, Chia-Yi, Lee, Yi-Hsuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3719842/ https://www.ncbi.nlm.nih.gov/pubmed/23904909 http://dx.doi.org/10.1371/journal.pone.0069019

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