Cargando…

Expression of pAkt affects p53 codon 72 polymorphism-based prediction of response to radiotherapy in nasopharyngeal carcinoma

BACKGROUND: Codon 72 (Arg/Pro), the most frequently studied single nucleotide polymorphism (SNP) of p53 to date, is associated with the ability of the gene to induce cell apoptosis. The PI3K/Akt pathway plays an essential role in the transcriptional activation function of p53, and is an important fa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xie, Xiaoxue, Wang, Hui, Jin, Hekun, Ouyang, Shuyu, Zhou, Jumei, Hu, Jun, Xi, Xuping, Luo, Junming, Zhang, Yingying, Hu, Bingqiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720183/ https://www.ncbi.nlm.nih.gov/pubmed/23663243 http://dx.doi.org/10.1186/1748-717X-8-117

Ejemplares similares

ERCC1 Cys8092Ala and XRCC1 Arg399Gln Polymorphisms Predict Progression-Free Survival after Curative Radiotherapy for Nasopharyngeal Carcinoma
por: Jin, Hekun, et al.
Publicado: (2014)

“p53 Polymorphism at Codon 72 and Breast Cancer” - Letter
por: Afzaljavan, Fahimeh, et al.
Publicado: (2017)

The significance of p53 codon 72 polymorphism for the development of cervical adenocarcinomas
por: Andersson, S, et al.
Publicado: (2001)

P53 codon 11, 72, and 248 gene polymorphisms in endometriosis
por: Hsieh, Yao-Yuan, et al.
Publicado: (2006)

Functional consequence of the p53 codon 72 polymorphism in colorectal cancer
por: Katkoori, Venkat R., et al.
Publicado: (2017)

Increased expression of pAKT is associated with radiation resistance in cervical cancer
por: Kim, T-J, et al.
Publicado: (2006)

Intrinsic Aerobic Capacity Affects Hippocampal pAkt and HSP72 Response to an Acute High Fat Diet and Heat Treatment in Rats
por: Gan, Li, et al.
Publicado: (2021)

Expression of the Androgen Receptor, pAkt, and pPTEN in Breast Cancer and Their Potential in Prognostication()
por: Sultana, Aisha, et al.
Publicado: (2014)

CELLFOOD™ induces apoptosis in human mesothelioma and colorectal cancer cells by modulating p53, c-myc and pAkt signaling pathways
por: Nuvoli, Barbara, et al.
Publicado: (2014)

p53 codon 72 polymorphism in vulval cancer and vulval intraepithelial neoplasia
por: Rosenthal, A N, et al.
Publicado: (2000)

p53 codon 72 polymorphism and risk of cervical carcinoma in Korean women.
por: Baek, W. K., et al.
Publicado: (2000)

p53 codon 72 polymorphism as a progression index for bladder cancer
por: LIN, HUNG-YU, et al.
Publicado: (2011)

Allelic Frequency of p53 Gene Codon 72 Polymorphism in Urologic Cancers
por: Wu, Wen‐Jeng, et al.
Publicado: (1995)

Differential Transcriptional Regulation of Polymorphic p53 Codon 72 in Metabolic Pathways
por: Kim, Bu-Yeo, et al.
Publicado: (2021)

P53 codon 72 polymorphism, human papillomavirus infection, and their interaction to oral carcinoma susceptibility
por: Hou, Jun, et al.
Publicado: (2015)

Correction: CELLFOOD™ induces apoptosis in human mesothelioma and colorectal cancer cells by modulating p53, c-myc and pAkt signaling pathways
por: Nuvoli, Barbara, et al.
Publicado: (2022)

p53 codon 72 polymorphism and Hematological Cancer Risk: An Update Meta-Analysis
por: Weng, Yu, et al.
Publicado: (2012)

p53 codon 72 polymorphism and breast cancer risk: A meta-analysis
por: HOU, JING, et al.
Publicado: (2013)

p53 codon 72 polymorphism association with head and neck squamous cell carcinoma
por: Mojtahedi, Zahra, et al.
Publicado: (2015)

Modulation of signaling cross-talk between pJNK and pAKT generates optimal apoptotic response
por: Biswas, Sharmila, et al.
Publicado: (2022)

Erythropoietin receptor regulates tumor mitochondrial biogenesis through iNOS and pAKT
por: Aboouf, Mostafa A., et al.
Publicado: (2022)

p53 Codon 72 Gene Polymorphism Studies and p53 Expression by Immunohistochemistry in Oral Lesions as Risk Factor for Malignancy
por: Tandon, Nishi, et al.
Publicado: (2017)

Risk of cervical cancer is not increased in Chinese carrying homozygous arginine at codon 72 of p53
por: Ngan, H Y S, et al.
Publicado: (1999)

p53 codon 72 polymorphism and coronary artery disease: Evidence of interaction with ACP(1)
por: Gloria-Bottini, Fulvia, et al.
Publicado: (2012)

Evaluation of polymorphism of P53 protein codon 72 in oral lichen planus by PCR technique
por: Tabatabaei, Seyed Hosein, et al.
Publicado: (2018)

Association between p53 Codon 72 (Arg72Pro) Polymorphism and Primary Open-Angle Glaucoma in Iranian Patients
por: Neamatzadeh, Hossein, et al.
Publicado: (2015)

pERK, pAKT and p53 as tissue biomarkers in erlotinib-treated patients with advanced pancreatic cancer: a translational subgroup analysis from AIO-PK0104
por: Ormanns, Steffen, et al.
Publicado: (2014)

Association of p53 codon72 Arg>Pro polymorphism with susceptibility to nasopharyngeal carcinoma: evidence from a case–control study and meta-analysis
por: Sahu, S K, et al.
Publicado: (2016)

No association betweenP53codon 72 polymorphism and risk of squamous cell carcinoma of the head and neck
por: Hamel, N, et al.
Publicado: (2000)

In B-CLL, the codon 72 polymorphic variants of p53 are not related to drug resistance and disease prognosis
por: Sturm, Isrid, et al.
Publicado: (2005)

Primary open angle glaucoma in a Caucasian population is associated with the p53 codon 72 polymorphism
por: Daugherty, Christopher L., et al.
Publicado: (2009)

Does p53 codon 72 polymorphism have a prognostic value in carcinoma of the vulva and vagina?
por: Qvick, Alvida, et al.
Publicado: (2017)

Common tumour p53 mutations in immortalized cells from Hupki mice heterozygous at codon 72.
por: Reinbold, M, et al.
Publicado: (2007)

Expression of pAkt is associated with a poor prognosis in Chinese women with invasive ductal breast cancer
por: Zhou, Ling, et al.
Publicado: (2018)

Identification of pAKT as a pharmacodynamic marker for MER kinase in human melanoma G361 cells
por: Chen, Yaoyu, et al.
Publicado: (2020)

Elevated serum expression of p53 and association of TP53 codon 72 polymorphisms with risk of cervical cancer in Bangladeshi women
por: Mostaid, Md Shaki, et al.
Publicado: (2021)

pERK/pAkt phenotyping in circulating tumor cells as a biomarker for sorafenib efficacy in patients with advanced hepatocellular carcinoma
por: Li, Jun, et al.
Publicado: (2015)

Detection of human papillomavirus DNA and p53 codon 72 polymorphism in prostate carcinomas of patients from Argentina
por: Leiros, Gustavo J, et al.
Publicado: (2005)

Relationship between p53 gene codon-72 polymorphisms and hypertrophic scar formation following caesarean section
por: GAO, JIANHUA, et al.
Publicado: (2014)

Role of p53 codon 72 polymorphism in chromosomal aberrations and mitotic index in patients with chronic hepatitis B
por: Akbaş, H., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_en5o31iq8qba1l812npcvaubng