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Expression of pAkt affects p53 codon 72 polymorphism-based prediction of response to radiotherapy in nasopharyngeal carcinoma

BACKGROUND: Codon 72 (Arg/Pro), the most frequently studied single nucleotide polymorphism (SNP) of p53 to date, is associated with the ability of the gene to induce cell apoptosis. The PI3K/Akt pathway plays an essential role in the transcriptional activation function of p53, and is an important fa...

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Detalles Bibliográficos
Autores principales:	Xie, Xiaoxue, Wang, Hui, Jin, Hekun, Ouyang, Shuyu, Zhou, Jumei, Hu, Jun, Xi, Xuping, Luo, Junming, Zhang, Yingying, Hu, Bingqiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720183/ https://www.ncbi.nlm.nih.gov/pubmed/23663243 http://dx.doi.org/10.1186/1748-717X-8-117

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