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Mitofusion-2-mediated alleviation of insulin resistance in rats through reduction in lipid intermediate accumulation in skeletal muscle
BACKGROUND: Increased lipid accumulation and mitochondrial dysfunction within skeletal muscle have been shown to be strongly associated with insulin resistance. However, the role of mitofusion-2 (MFN2), a key factor in mitochondrial function and energy metabolism, in skeletal muscle lipid intermedia...
Autores principales: | Zhang, Xuemei, Wang, Chao, Song, Guangyao, Gan, Kexin, Kong, Dexian, Nie, Qian, Ren, Luping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720227/ https://www.ncbi.nlm.nih.gov/pubmed/23815800 http://dx.doi.org/10.1186/1423-0127-20-45 |
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