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Anthranilate Fluorescence Marks a Calcium-Propagated Necrotic Wave That Promotes Organismal Death in C. elegans
For cells the passage from life to death can involve a regulated, programmed transition. In contrast to cell death, the mechanisms of systemic collapse underlying organismal death remain poorly understood. Here we present evidence of a cascade of cell death involving the calpain-cathepsin necrosis p...
Autores principales: | Coburn, Cassandra, Allman, Erik, Mahanti, Parag, Benedetto, Alexandre, Cabreiro, Filipe, Pincus, Zachary, Matthijssens, Filip, Araiz, Caroline, Mandel, Abraham, Vlachos, Manolis, Edwards, Sally-Anne, Fischer, Grahame, Davidson, Alexander, Pryor, Rosina E., Stevens, Ailsa, Slack, Frank J., Tavernarakis, Nektarios, Braeckman, Bart P., Schroeder, Frank C., Nehrke, Keith, Gems, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720247/ https://www.ncbi.nlm.nih.gov/pubmed/23935448 http://dx.doi.org/10.1371/journal.pbio.1001613 |
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