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Speech disturbance at stroke onset is correlated with stroke early mortality

BACKGROUND: Speech disturbance is a common symptom of stroke and is important as a prompt identifier of the event. The frequency of the symptom among each stroke subtype, differences between patients with and without speech disturbance and its correlation to early mortality remain unclear. METHODS:...

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Autores principales: Shigematsu, Kazuo, Nakano, Hiromi, Watanabe, Yoshiyuki, Sekimoto, Tatsuyuki, Shimizu, Kouichiro, Nishizawa, Akihiko, Okumura, Atsushi, Makino, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720260/
https://www.ncbi.nlm.nih.gov/pubmed/23855651
http://dx.doi.org/10.1186/1471-2377-13-87
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author Shigematsu, Kazuo
Nakano, Hiromi
Watanabe, Yoshiyuki
Sekimoto, Tatsuyuki
Shimizu, Kouichiro
Nishizawa, Akihiko
Okumura, Atsushi
Makino, Masahiro
author_facet Shigematsu, Kazuo
Nakano, Hiromi
Watanabe, Yoshiyuki
Sekimoto, Tatsuyuki
Shimizu, Kouichiro
Nishizawa, Akihiko
Okumura, Atsushi
Makino, Masahiro
author_sort Shigematsu, Kazuo
collection PubMed
description BACKGROUND: Speech disturbance is a common symptom of stroke and is important as a prompt identifier of the event. The frequency of the symptom among each stroke subtype, differences between patients with and without speech disturbance and its correlation to early mortality remain unclear. METHODS: The Kyoto prefecture of Japan has established a registry to enroll new stroke patients in cooperation with the Kyoto Medical Association and its affiliated hospitals. It is named the Kyoto Stroke Registry (KSR). We confirmed the existence or absence of speech disturbance in 1693 stroke patients registered to the KSR and investigated associations between speech disturbance and other characteristics. RESULTS: Speech disturbance was observed in 52.6% of cerebral infarction (CI), 47.5% of cerebral hemorrhage (CH), and 8.0% of subarachnoid hemorrhage (SAH) cases. Characteristics showing statistically significant differences between patients with and without speech disturbance and patients were age, blood pressure, history of hypertension, arrhythmia and diabetes mellitus, habit of tobacco and alcohol, and paresis. Mortality rates of patients with/without speech disturbance were 5.2%/1.2% for CI, 12.5% /4.1% for CH, and 62.5%/ 9.0% for SAH. Adjusted hazard ratios were 2.63 (1.14-6.13, p = 0.024) in CI, 4.15 (1.41-12.23, p = 0.010) in CH, and 20.46 (4.40-95.07, p < 0.001) in SAH). CONCLUSION: Speech disturbance was frequently observed in stroke patients at the onset and therefore could be useful to identify the problem at the earliest stage. Hazard ratio for death was higher in stroke patients with speech disturbance than patients without. Speech disturbance is a prompt predictor of stroke early mortality. Hiromi Nakano, Yoshiyuki Watanabe, Tatsuyuki Sekimoto, Kouichiro Shimizu, Akihiko Nishizawa, Atsushi Okumura and Masahiro Makino contributed equally to this work.
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spelling pubmed-37202602013-07-24 Speech disturbance at stroke onset is correlated with stroke early mortality Shigematsu, Kazuo Nakano, Hiromi Watanabe, Yoshiyuki Sekimoto, Tatsuyuki Shimizu, Kouichiro Nishizawa, Akihiko Okumura, Atsushi Makino, Masahiro BMC Neurol Research Article BACKGROUND: Speech disturbance is a common symptom of stroke and is important as a prompt identifier of the event. The frequency of the symptom among each stroke subtype, differences between patients with and without speech disturbance and its correlation to early mortality remain unclear. METHODS: The Kyoto prefecture of Japan has established a registry to enroll new stroke patients in cooperation with the Kyoto Medical Association and its affiliated hospitals. It is named the Kyoto Stroke Registry (KSR). We confirmed the existence or absence of speech disturbance in 1693 stroke patients registered to the KSR and investigated associations between speech disturbance and other characteristics. RESULTS: Speech disturbance was observed in 52.6% of cerebral infarction (CI), 47.5% of cerebral hemorrhage (CH), and 8.0% of subarachnoid hemorrhage (SAH) cases. Characteristics showing statistically significant differences between patients with and without speech disturbance and patients were age, blood pressure, history of hypertension, arrhythmia and diabetes mellitus, habit of tobacco and alcohol, and paresis. Mortality rates of patients with/without speech disturbance were 5.2%/1.2% for CI, 12.5% /4.1% for CH, and 62.5%/ 9.0% for SAH. Adjusted hazard ratios were 2.63 (1.14-6.13, p = 0.024) in CI, 4.15 (1.41-12.23, p = 0.010) in CH, and 20.46 (4.40-95.07, p < 0.001) in SAH). CONCLUSION: Speech disturbance was frequently observed in stroke patients at the onset and therefore could be useful to identify the problem at the earliest stage. Hazard ratio for death was higher in stroke patients with speech disturbance than patients without. Speech disturbance is a prompt predictor of stroke early mortality. Hiromi Nakano, Yoshiyuki Watanabe, Tatsuyuki Sekimoto, Kouichiro Shimizu, Akihiko Nishizawa, Atsushi Okumura and Masahiro Makino contributed equally to this work. BioMed Central 2013-07-15 /pmc/articles/PMC3720260/ /pubmed/23855651 http://dx.doi.org/10.1186/1471-2377-13-87 Text en Copyright © 2013 Shigematsu et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Shigematsu, Kazuo
Nakano, Hiromi
Watanabe, Yoshiyuki
Sekimoto, Tatsuyuki
Shimizu, Kouichiro
Nishizawa, Akihiko
Okumura, Atsushi
Makino, Masahiro
Speech disturbance at stroke onset is correlated with stroke early mortality
title Speech disturbance at stroke onset is correlated with stroke early mortality
title_full Speech disturbance at stroke onset is correlated with stroke early mortality
title_fullStr Speech disturbance at stroke onset is correlated with stroke early mortality
title_full_unstemmed Speech disturbance at stroke onset is correlated with stroke early mortality
title_short Speech disturbance at stroke onset is correlated with stroke early mortality
title_sort speech disturbance at stroke onset is correlated with stroke early mortality
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720260/
https://www.ncbi.nlm.nih.gov/pubmed/23855651
http://dx.doi.org/10.1186/1471-2377-13-87
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