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Localization of BRCA1 protein in breast cancer tissue and cell lines with mutations

BACKGROUND: The breast and ovarian cancer susceptibility gene (BRCA1) encodes a tumor suppressor. The BRCA1 protein is found primarily in cell nuclei and plays an important role in the DNA damage response and transcriptional regulation. Deficiencies in DNA repair capabilities have been associated wi...

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Detalles Bibliográficos
Autores principales:	Tulchin, Natalie, Ornstein, Leonard, Dikman, Steven, Strauchen, James, Jaffer, Shabnam, Nagi, Chandandeep, Bleiweiss, Ira, Kornreich, Ruth, Edelmann, Lisa, Brown, Karen, Bodian, Carol, Nair, Venugopalan D, Chambon, Monique, Woods, Nicholas T, Monteiro, Alvaro NA
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720266/ https://www.ncbi.nlm.nih.gov/pubmed/23855721 http://dx.doi.org/10.1186/1475-2867-13-70

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