Melittin Suppresses HIF-1α/VEGF Expression through Inhibition of ERK and mTOR/p70S6K Pathway in Human Cervical Carcinoma Cells

OBJECTIVE: Melittin (MEL), a major component of bee venom, has been associated with various diseases including arthritis, rheumatism and various cancers. In this study, the anti-angiogenic effects of MEL in CaSki cells that were responsive to the epidermal growth factor (EGF) were examined. METHODOL...

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Detalles Bibliográficos
Autores principales: Shin, Jae-Moon, Jeong, Yun-Jeong, Cho, Hyun-Ji, Park, Kwan-Kyu, Chung, Il-Kyung, Lee, In-Kyu, Kwak, Jong-Young, Chang, Hyeun-Wook, Kim, Cheorl-Ho, Moon, Sung-Kwon, Kim, Wun-Jae, Choi, Yung-Hyun, Chang, Young-Chae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720276/
https://www.ncbi.nlm.nih.gov/pubmed/23936001
http://dx.doi.org/10.1371/journal.pone.0069380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720276/
https://www.ncbi.nlm.nih.gov/pubmed/23936001
http://dx.doi.org/10.1371/journal.pone.0069380

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