Nemo-Like Kinase Associated with Proliferation and Apoptosis by c-Myb Degradation in Breast Cancer

Nemo-like kinase (NLK), a mediator of the Wnt signaling pathway, binds directly to c-Myb, leading to its phosphorylation, ubiquitination and proteasome-dependent degradation. NLK was significantly downregulated in the breast cancer tissues compared to corresponding normal tissues. NLK expression was...

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Detalles Bibliográficos
Autores principales: Huang, Yeqing, Jiang, Ying, Lu, Weiqi, Zhang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720543/
https://www.ncbi.nlm.nih.gov/pubmed/23935942
http://dx.doi.org/10.1371/journal.pone.0069148

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720543/
https://www.ncbi.nlm.nih.gov/pubmed/23935942
http://dx.doi.org/10.1371/journal.pone.0069148

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