Contributions to osteoclast biology from Japan

Bone is a dynamic tissue, in which bone formation by osteoblasts and bone resorption by osteoclasts continue throughout life. In 1998, we molecularly cloned osteoclast differentiation factor (ODF), a long-thought factor responsible for osteoclast formation. This review article describes how Japanese...

Descripción completa

Detalles Bibliográficos
Autores principales: Suda, Tatsuo, Takahashi, Naoyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japan Academy 2008
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720546/
https://www.ncbi.nlm.nih.gov/pubmed/19075515
http://dx.doi.org/10.2183/pjab/84.419
Descripción
Sumario:Bone is a dynamic tissue, in which bone formation by osteoblasts and bone resorption by osteoclasts continue throughout life. In 1998, we molecularly cloned osteoclast differentiation factor (ODF), a long-thought factor responsible for osteoclast formation. This review article describes how Japanese scientists contributed to osteoclast biology before and after the discovery of ODF. This review article is based on the Louis V. Avioli Memorial Lecture of the American Society for Bone and Mineral Research (ASBMR) held in Honolulu in September, 2007.

Ejemplares similares