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Selection of pfdhfr/pfdhps alleles and declining artesunate/sulphadoxine-pyrimethamine efficacy against Plasmodium falciparum eight years after deployment in eastern Sudan

BACKGROUND: Artesunate/sulphadoxine-pyrimethamine (AS/SP) has been the first-line treatment for falciparum malaria in Sudan since 2004. The impact of this combination on anti-malarial resistance-associated molecular markers has not been investigated. In this study, an evaluation of the efficacy and...

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Detalles Bibliográficos
Autores principales:	Gadalla, Nahla B, Abdallah, Tajeldin M, Atwal, Sharanjeet, Sutherland, Colin J, Adam, Ishag
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720549/ https://www.ncbi.nlm.nih.gov/pubmed/23870667 http://dx.doi.org/10.1186/1475-2875-12-255

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