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Roflumilast Inhibits Respiratory Syncytial Virus Infection in Human Differentiated Bronchial Epithelial Cells

Respiratory syncytial virus (RSV) causes acute exacerbations in COPD and asthma. RSV infects bronchial epithelial cells (HBE) that trigger RSV associated lung pathology. This study explores whether the phosphodiesterase 4 (PDE4) inhibitor Roflumilast N-oxide (RNO), alters RSV infection of well-diffe...

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Detalles Bibliográficos
Autores principales:	Mata, Manuel, Martinez, Isidoro, Melero, Jose A., Tenor, Herman, Cortijo, Julio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720563/ https://www.ncbi.nlm.nih.gov/pubmed/23936072 http://dx.doi.org/10.1371/journal.pone.0069670

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