Dysfunctional oxidative phosphorylation makes malignant melanoma cells addicted to glycolysis driven by the (V600E)BRAF oncogene

Oncogene addiction describes how cancer cells exhibit dependence on single oncogenes to escape apoptosis and senescence. While oncogene addiction constitutes the basis for new cancer treatment strategies targeting individual kinases and pathways activated by oncogenic mutations, the biochemical basi...

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Detalles Bibliográficos
Autores principales: Hall, Arnaldur, Meyle, Kathrine Damm, Lange, Marina Krarup, Klima, Martin, Sanderhoff, May, Dahl, Christina, Abildgaard, Cecilie, Thorup, Katrine, Moghimi, Seyed Moein, Jensen, Per Bo, Bartek, Jiri, Guldberg, Per, Christensen, Claus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720606/
https://www.ncbi.nlm.nih.gov/pubmed/23603840

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