Cargando…

Challenges in Using Cultured Primary Rodent Hepatocytes or Cell Lines to Study Hepatic HDL Receptor SR-BI Regulation by Its Cytoplasmic Adaptor PDZK1

BACKGROUND: PDZK1 is a four PDZ-domain containing cytoplasmic protein that binds to a variety of membrane proteins via their C-termini and can influence the abundance, localization and/or function of its target proteins. One of these targets in hepatocytes in vivo is the HDL receptor SR-BI. Normal h...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tsukamoto, Kosuke, Buck, Lorenna, Inman, Walker, Griffith, Linda, Kocher, Olivier, Krieger, Monty
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720616/ https://www.ncbi.nlm.nih.gov/pubmed/23936087 http://dx.doi.org/10.1371/journal.pone.0069725

Ejemplares similares

SR-BI Mediated Transcytosis of HDL in Brain Microvascular Endothelial Cells Is Independent of Caveolin, Clathrin, and PDZK1
por: Fung, Karen Y., et al.
Publicado: (2017)

The SR-BI Partner PDZK1 Facilitates Hepatitis C Virus Entry
por: Eyre, Nicholas S., et al.
Publicado: (2010)

Molecular Analysis of the Prostacyclin Receptor’s Interaction with the PDZ1 Domain of Its Adaptor Protein PDZK1
por: Birrane, Gabriel, et al.
Publicado: (2013)

Loss of PDZK1 Causes Coronary Artery Occlusion and Myocardial Infarction in Paigen Diet-Fed Apolipoprotein E Deficient Mice
por: Yesilaltay, Ayce, et al.
Publicado: (2009)

Advanced oxidation protein products are antagonists of the HDL receptor SR-BI
por: Marsche, Gunther, et al.
Publicado: (2009)

ATP Synthase β-Chain Overexpression in SR-BI Knockout Mice Increases HDL Uptake and Reduces Plasma HDL Level
por: Song, Kexiu, et al.
Publicado: (2014)

Downregulation of the NHE3-Binding PDZ-Adaptor Protein PDZK1 Expression during Cytokine-Induced Inflammation in Interleukin-10–Deficient Mice
por: Lenzen, Henrike, et al.
Publicado: (2012)

Evidence for a causal link between adaptor protein PDZK1 downregulation and Na(+)/H(+) exchanger NHE3 dysfunction in human and murine colitis
por: Yeruva, Sunil, et al.
Publicado: (2014)

IL-1β-Induced Downregulation of the Multifunctional PDZ Adaptor PDZK1 Is Attenuated by ERK Inhibition, RXRα, or PPARα Stimulation in Enterocytes
por: Luo, Min, et al.
Publicado: (2017)

Mechanism of PDZK1 in Hepatocellular Carcinoma Complicated with Hyperuricemia
por: Guo, Linqi, et al.
Publicado: (2022)

Indolinyl-Thiazole Based Inhibitors of Scavenger Receptor-BI (SR-BI)-Mediated Lipid Transport
por: Dockendorff, Chris, et al.
Publicado: (2015)

Diabetic HDL Is Dysfunctional in Stimulating Endothelial Cell Migration and Proliferation Due to Down Regulation of SR-BI Expression
por: Pan, Bing, et al.
Publicado: (2012)

The Distinct Role of the HDL Receptor SR-BI in Cholesterol Homeostasis of Human Placental Arterial and Venous Endothelial Cells
por: Strahlhofer-Augsten, Manuela, et al.
Publicado: (2022)

Xestospongia muta Fraction-7 and Linoleic Acid: Effects on SR-BI Gene Expression and HDL Cholesterol Uptake
por: Azemi, Nurul Adila, et al.
Publicado: (2022)

Increased apolipoprotein M induced by lack of scavenger receptor BI is not activated via HDL-mediated cholesterol uptake in hepatocytes
por: Feng, Yue-Hua, et al.
Publicado: (2018)

Modulators of Protein Kinase C Affect SR-BI-Dependent HDL Lipid Uptake in Transfected HepG2 Cells
por: Brunet, Rachelle, et al.
Publicado: (2011)

The HDL receptor SR-BI is associated with human prostate cancer progression and plays a possible role in establishing androgen independence
por: Schörghofer, David, et al.
Publicado: (2015)

ABCA1, ABCG1 and SR-BI: hormonal regulation in primary rat hepatocytes and human cell lines
por: Sporstøl, Marita, et al.
Publicado: (2007)

(225)Ac-rHDL Nanoparticles: A Potential Agent for Targeted Alpha-Particle Therapy of Tumors Overexpressing SR-BI Proteins
por: Hernández-Jiménez, Tania, et al.
Publicado: (2022)

Hepatocyte ABCA1 deficiency is associated with reduced HDL sphingolipids
por: Othman, Alaa, et al.
Publicado: (2023)

The cargo protein MAP17 (PDZK1IP1) regulates the immune microenvironment
por: García-Heredia, José M., et al.
Publicado: (2017)

Efficacy of bortezomib in sarcomas with high levels of MAP17 (PDZK1IP1)
por: Perez, Marco, et al.
Publicado: (2016)

SR-BI/CD36 Chimeric Receptors Define Extracellular Subdomains of SR-BI Critical for Cholesterol Transport
por: Kartz, Gabriella A., et al.
Publicado: (2014)

The meiotic LINC complex component KASH5 is an activating adaptor for cytoplasmic dynein
por: Garner, Kirsten E.L., et al.
Publicado: (2023)

Altered Visual Function in a Larval Zebrafish Knockout of Neurodevelopmental Risk Gene pdzk1
por: Xie, Jiaheng, et al.
Publicado: (2021)

OBSERVATIONS ON THE UNUSUAL CYTOPLASMIC LACUNAE OF THE PORCINE HEPATOCYTE
por: Searle, Roger F.
Publicado: (1972)

SR proteins are NXF1 adaptors that link alternative RNA processing to mRNA export
por: Müller-McNicoll, Michaela, et al.
Publicado: (2016)

SR-B1’s Next Top Model: Structural Perspectives on the Functions of the HDL Receptor
por: Powers, Hayley R., et al.
Publicado: (2022)

A Regulated Complex of the Scaffolding Proteins PDZK1 and EBP50 with Ezrin Contribute to Microvillar Organization
por: LaLonde, David P., et al.
Publicado: (2010)

Targeting SR-BI for Cancer Diagnostics, Imaging and Therapy
por: Rajora, Maneesha A., et al.
Publicado: (2016)

Large enhancement of superconducting transition temperature of SrBi3 induced by Na substitution for Sr
por: Iyo, Akira, et al.
Publicado: (2015)

Interaction of the human prostacyclin receptor with the PDZ adapter protein PDZK1: role in endothelial cell migration and angiogenesis
por: Turner, Elizebeth C., et al.
Publicado: (2011)

PDZK1 Prevents Neointima Formation via Suppression of Breakpoint Cluster Region Kinase in Vascular Smooth Muscle
por: Lee, Wan Ru, et al.
Publicado: (2015)

Hematopoietic cytoplasmic adaptor protein Hem1 promotes osteoclast fusion and bone resorption in mice
por: Wang, Xiaoyan, et al.
Publicado: (2022)

Lipoprotein Glomerulopathy-Like Lesions in Atherosclerotic Mice Defected With HDL Receptor SR-B1
por: Liao, Jiawei, et al.
Publicado: (2021)

HDL-Chitosan Nanoparticles for siRNA Delivery as an SR-B1 Receptor Targeted System
por: Masimov, Rasim, et al.
Publicado: (2023)

Hepatocyte ATF3 protects against atherosclerosis by regulating HDL and bile acid metabolism
por: Xu, Yanyong, et al.
Publicado: (2021)

HDL functionality is dependent on hepatocyte stress defense factors Nrf1 and Nrf2
por: Trites, Michael J., et al.
Publicado: (2023)

The Effect of Bi-Sr and Ca-Sr Interactions on the Microstructure and Tensile Properties of Al-Si-Based Alloys
por: Samuel, Agnes M., et al.
Publicado: (2016)

Interplay of Dirac electrons and magnetism in CaMnBi(2) and SrMnBi(2)
por: Zhang, Anmin, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_7ao9t39glcfp2mgr45bngn7d3n