Relationship between PTEN, DNA Mismatch Repair, and Tumor Histotype in Endometrial Carcinoma: Retained Positive Expression of PTEN Preferentially Identifies Sporadic Non-Endometrioid Carcinomas

Loss of PTEN (phosphatase and tensin homolog) expression and microsatellite instability are two of the more common molecular alterations in endometrial carcinoma. From the published literature, it is controversial as to whether there is a relationship between these different molecular mechanisms. Th...

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Detalles Bibliográficos
Autores principales: Djordjevic, Bojana, Barkoh, Bedia A., Luthra, Rajyalakshmi, Broaddus, Russell R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720775/
https://www.ncbi.nlm.nih.gov/pubmed/23599155
http://dx.doi.org/10.1038/modpathol.2013.67

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