Optimization of a Widefield Structured Illumination Microscope for Non-Destructive Assessment and Quantification of Nuclear Features in Tumor Margins of a Primary Mouse Model of Sarcoma

Cancer is associated with specific cellular morphological changes, such as increased nuclear size and crowding from rapidly proliferating cells. In situ tissue imaging using fluorescent stains may be useful for intraoperative detection of residual cancer in surgical tumor margins. We developed a wid...

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Detalles Bibliográficos
Autores principales: Fu, Henry L., Mueller, Jenna L., Javid, Melodi P., Mito, Jeffrey K., Kirsch, David G., Ramanujam, Nimmi, Brown, J. Quincy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720887/
https://www.ncbi.nlm.nih.gov/pubmed/23894357
http://dx.doi.org/10.1371/journal.pone.0068868

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