Cargando…

Ferristatin II Promotes Degradation of Transferrin Receptor-1 In Vitro and In Vivo

Previous studies have shown that the small molecule iron transport inhibitor ferristatin (NSC30611) acts by down-regulating transferrin receptor-1 (TfR1) via receptor degradation. In this investigation, we show that another small molecule, ferristatin II (NSC8679), acts in a similar manner to degrad...

Descripción completa

Detalles Bibliográficos
Autores principales:	Byrne, Shaina L., Buckett, Peter D., Kim, Jonghan, Luo, Flora, Sanford, Jack, Chen, Juxing, Enns, Caroline, Wessling-Resnick, Marianne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720890/ https://www.ncbi.nlm.nih.gov/pubmed/23894616 http://dx.doi.org/10.1371/journal.pone.0070199

Ejemplares similares

Absorption of Manganese and Iron in a Mouse Model of Hemochromatosis
por: Kim, Jonghan, et al.
Publicado: (2013)

Ferristatin II Efficiently Inhibits SARS-CoV-2 Replication in Vero Cells
por: Sokolov, Alexey, et al.
Publicado: (2022)

The Role of Iron Metabolism in Lung Inflammation and Injury
por: Kim, Jonghan, et al.
Publicado: (2012)

Iron-Responsive Olfactory Uptake of Manganese Improves Motor Function Deficits Associated with Iron Deficiency
por: Kim, Jonghan, et al.
Publicado: (2012)

N-Linked Glycosylation Is Required for Transferrin-Induced Stabilization of Transferrin Receptor 2, but Not for Transferrin Binding or Trafficking to the Cell Surface
por: Zhao, Ningning, et al.
Publicado: (2013)

The role of hepatic transferrin receptor 2 in the regulation of iron homeostasis in the body
por: Worthen, Christal A., et al.
Publicado: (2014)

The small molecule, genistein, increases hepcidin expression in human hepatocytes
por: Zhen, Aileen W, et al.
Publicado: (2013)

The First Transmembrane Domain of Lipid Phosphatase SAC1 Promotes Golgi Localization
por: Wang, Jinzhi, et al.
Publicado: (2013)

Pathophysiology of the Belgrade rat
por: Veuthey, Tania, et al.
Publicado: (2014)

Brain Iron Homeostasis: A Focus on Microglial Iron
por: Nnah, Israel C., et al.
Publicado: (2018)

Soluble Form of Canine Transferrin Receptor Inhibits Canine Parvovirus Infection In Vitro and In Vivo
por: Wen, Jiexia, et al.
Publicado: (2013)

Enhanced antitumor efficacy of cisplatin for treating ovarian cancer in vitro and in vivo via transferrin binding
por: Peng, Huifang, et al.
Publicado: (2017)

Duodenal macrophages control dietary iron absorption via local degradation of transferrin
por: Sukhbaatar, Nyamdelger, et al.
Publicado: (2023)

Distribution of manganese and other biometals in flatiron mice
por: Seo, Young Ah, et al.
Publicado: (2015)

Functional Expression Cloning and Characterization of SFT, a Stimulator of Fe Transport
por: Gutierrez, Jesus A., et al.
Publicado: (1997)

Regulation of divalent metal transporter-1 by serine phosphorylation
por: Seo, Young Ah, et al.
Publicado: (2016)

Rapid endocytosis of the transferrin receptor in the absence of bound transferrin
Publicado: (1985)

WDR45 Mutation Impairs the Autophagic Degradation of Transferrin Receptor and Promotes Ferroptosis
por: Xiong, Qiuhong, et al.
Publicado: (2021)

Role of transferrin, transferrin receptors, and iron in macrophage listericidal activity
Publicado: (1991)

The structural basis of transferrin sequestration by transferrin-binding protein B
por: Calmettes, Charles, et al.
Publicado: (2012)

Receptor-mediated endocytosis of transferrin and recycling of the transferrin receptor in rat reticulocytes
Publicado: (1983)

Transferrin-binding protein complex is the receptor for transferrin uptake in Trypanosoma brucei
Publicado: (1995)

In vitro and in vivo studies on the degradation of metallothionein.
por: Klaassen, C D, et al.
Publicado: (1994)

Transferrin Receptors in Erythropoiesis
por: Richard, Cyrielle, et al.
Publicado: (2020)

The Invasion and Reproductive Toxicity of QDs-Transferrin Bioconjugates on Preantral Follicle in vitro
por: Xu, Gaixia, et al.
Publicado: (2012)

Preparation, characterization and in vitro efficacy of magnetic nanoliposomes containing the artemisinin and transferrin
por: Gharib, Amir, et al.
Publicado: (2014)

Adenocarcinoma cells isolated from patients in the presence of cerium and transferrin in vitro
por: Zende-Del, A, et al.
Publicado: (2015)

Blocking transferrin receptor inhibits the growth of lung adenocarcinoma cells in vitro
por: Wu, Yihe, et al.
Publicado: (2017)

Internalization and processing of transferrin and the transferrin receptor in human carcinoma A431 cells
Publicado: (1983)

Role of Fe, Transferrin and Transferrin Receptor in Anti-Tumor Effect of Vitamin C
por: Qiu, Jia, et al.
Publicado: (2022)

Associations of iron metabolism genes with blood manganese levels: a population-based study with validation data from animal models
por: Claus Henn, Birgit, et al.
Publicado: (2011)

Effect of transferrin glycation induced by high glucose on HK-2 cells in vitro
por: Ma, Yanqi, et al.
Publicado: (2023)

Prooxidant activity of transferrin and lactoferrin
Publicado: (1990)

The Oxidative Function of Diferric Transferrin
por: Crane, Frederick L., et al.
Publicado: (2012)

Transferrin changes in haemodialysed patients
por: Formanowicz, Dorota, et al.
Publicado: (2011)

Transferrin Enhances Neuronal Differentiation
por: Pérez, María Julia, et al.
Publicado: (2023)

Calpain-Mediated Degradation of Drebrin by Excitotoxicity In vitro and In vivo
por: Chimura, Takahiko, et al.
Publicado: (2015)

In vitro and in vivo degradation of microfiber bioresorbable coronary scaffold
por: Huang, Chi‐Hung, et al.
Publicado: (2017)

Electrospun Polycaprolactone (PCL) Degradation: An In Vitro and In Vivo Study
por: Dias, Juliana R., et al.
Publicado: (2022)

Role of Insulin-Transferrin-Selenium in Auricular Chondrocyte Proliferation and Engineered Cartilage Formation in Vitro
por: Liu, Xia, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_8rhq48iekajem9mehuqkrl991u