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Deficiency of Smad7 Enhances Cardiac Remodeling Induced by Angiotensin II Infusion in a Mouse Model of Hypertension

Smad7 has been shown to negatively regulate fibrosis and inflammation, but its role in angiotensin II (Ang II)-induced hypertensive cardiac remodeling remains unknown. Therefore, the present study investigated the role of Smad7 in hypertensive cardiopathy induced by angiotensin II infusion. Hyperten...

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Detalles Bibliográficos
Autores principales:	Wei, Li Hua, Huang, Xiao Ru, Zhang, Yang, Li, You Qi, Chen, Hai-yong, Heuchel, Rainer, Yan, Bryan P., Yu, Cheuk-Man, Lan, Hui Yao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720917/ https://www.ncbi.nlm.nih.gov/pubmed/23894614 http://dx.doi.org/10.1371/journal.pone.0070195

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