Cargando…

A Dual Role for SAGA-Associated Factor 29 (SGF29) in ER Stress Survival by Coordination of Both Histone H3 Acetylation and Histone H3 Lysine-4 Trimethylation

The SGF29 protein binds to tri-methylated lysine-4 of histone H3 (H3K4me3), which is a histone modification associated with active promoters. Human SGF29 is a subunit of the histone acetyltransferase module of the SAGA (Spt-Ada-Gcn5 acetyltransferase) and ATAC (Ada-Two-A-containing 2A) co-activator...

Descripción completa

Detalles Bibliográficos
Autores principales: Schram, Andrea W., Baas, Roy, Jansen, Pascal W. T. C., Riss, Anne, Tora, Laszlo, Vermeulen, Michiel, Timmers, H. Th. Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720948/
https://www.ncbi.nlm.nih.gov/pubmed/23894581
http://dx.doi.org/10.1371/journal.pone.0070035