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The MDM2-p53 pathway revisited

The p53 tumor suppressor is a key transcription factor regulating cellular pathways such as DNA repair, cell cycle, apoptosis, angiogenesis, and senescence. It acts as an important defense mechanism against cancer onset and progression, and is negatively regulated by interaction with the oncoprotein...

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Detalles Bibliográficos
Autores principales:	Nag, Subhasree, Qin, Jiangjiang, Srivenugopal, Kalkunte S., Wang, Minghai, Zhang, Ruiwen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Editorial Department of Journal of Biomedical Research 2013
Materias:	Invited Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3721034/ https://www.ncbi.nlm.nih.gov/pubmed/23885265 http://dx.doi.org/10.7555/JBR.27.20130030

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