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A patterned recombinant human IgM guides neurite outgrowth of CNS neurons
Matrix molecules convey biochemical and physical guiding signals to neurons in the central nervous system (CNS) and shape the trajectory of neuronal fibers that constitute neural networks. We have developed recombinant human IgMs that bind to epitopes on neural cells, with the aim of treating neurol...
Autores principales: | Xu, Xiaohua, Wittenberg, Nathan J., Jordan, Luke R., Kumar, Shailabh, Watzlawik, Jens O., Warrington, Arthur E., Oh, Sang-Hyun, Rodriguez, Moses |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3721078/ https://www.ncbi.nlm.nih.gov/pubmed/23881231 http://dx.doi.org/10.1038/srep02267 |
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