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Self-Association of Okadaic Acid: Structural and Pharmacological Significance
Okadaic acid (OA) has been an invaluable pharmacological tool in the study of cellular signaling. The great affinity of this polyether for its targets together with its high specificity to inhibit certain protein phosphatases enables the differential study of these proteins. Crystallographic structu...
Autores principales: | Cruz, Patricia G., Norte, Manuel, Hernández Creus, Alberto, Fernández, José J., Hernández Daranas, Antonio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3721210/ https://www.ncbi.nlm.nih.gov/pubmed/23760016 http://dx.doi.org/10.3390/md11061866 |
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