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Tetrodotoxin Blockade on Canine Cardiac L-Type Ca(2+) Channels Depends on pH and Redox Potential
Tetrodotoxin (TTX) is believed to be one of the most selective inhibitors of voltage-gated fast Na(+) channels in excitable tissues. Recently, however, TTX has been shown to block L-type Ca(2+) current (I(Ca)) in canine cardiac cells. In the present study, the TTX-sensitivity of I(Ca) was studied in...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3721225/ https://www.ncbi.nlm.nih.gov/pubmed/23771047 http://dx.doi.org/10.3390/md11062140 |