FOXO3 expression during colorectal cancer progression: biomarker potential reflects a tumour suppressor role

BACKGROUND: In previous studies, the Forkhead/winged-helix-box-class-O3 (FOXO3) transcription factor has displayed both tumour suppressive and metastasis-promoting properties. To clarify its role in human colorectal cancer (CRC) progression, we examined in vivo FOXO3 expression at key points of the...

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Detalles Bibliográficos
Autores principales: Bullock, M D, Bruce, A, Sreekumar, R, Curtis, N, Cheung, T, Reading, I, Primrose, J N, Ottensmeier, C, Packham, G K, Thomas, G, Mirnezami, A H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3721407/
https://www.ncbi.nlm.nih.gov/pubmed/23828518
http://dx.doi.org/10.1038/bjc.2013.355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3721407/
https://www.ncbi.nlm.nih.gov/pubmed/23828518
http://dx.doi.org/10.1038/bjc.2013.355

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