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FOXO3 expression during colorectal cancer progression: biomarker potential reflects a tumour suppressor role

BACKGROUND: In previous studies, the Forkhead/winged-helix-box-class-O3 (FOXO3) transcription factor has displayed both tumour suppressive and metastasis-promoting properties. To clarify its role in human colorectal cancer (CRC) progression, we examined in vivo FOXO3 expression at key points of the...

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Detalles Bibliográficos
Autores principales:	Bullock, M D, Bruce, A, Sreekumar, R, Curtis, N, Cheung, T, Reading, I, Primrose, J N, Ottensmeier, C, Packham, G K, Thomas, G, Mirnezami, A H
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3721407/ https://www.ncbi.nlm.nih.gov/pubmed/23828518 http://dx.doi.org/10.1038/bjc.2013.355

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