Matrix metalloproteinase 13 modulates intestinal epithelial barrier integrity in inflammatory diseases by activating TNF

Several pathological processes, such as sepsis and inflammatory bowel disease (IBD), are associated with impairment of intestinal epithelial barrier. Here, we investigated the role of matrix metalloproteinase MMP13 in these diseases. We observed that MMP13(−/−) mice display a strong protection in LP...

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Detalles Bibliográficos
Autores principales: Vandenbroucke, Roosmarijn E, Dejonckheere, Eline, Van Hauwermeiren, Filip, Lodens, Sofie, De Rycke, Riet, Van Wonterghem, Elien, Staes, An, Gevaert, Kris, López-Otin, Carlos, Libert, Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3721470/
https://www.ncbi.nlm.nih.gov/pubmed/23723167
http://dx.doi.org/10.1002/emmm.201202100

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