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Usp18 deficient mammary epithelial cells create an antitumour environment driven by hypersensitivity to IFN-λ and elevated secretion of Cxcl10
The theory of cancer immunoediting refers to mechanisms by which the immune system can suppress or promote tumour progression. A major challenge for the development of novel cancer immunotherapies is to find ways to exploit the immune system's antitumour activity while concomitantly reducing it...
Autores principales: | Burkart, Christoph, Arimoto, Kei-ichiro, Tang, Tingdong, Cong, Xiuli, Xiao, Nengming, Liu, Yun-Cai, Kotenko, Sergei V, Ellies, Lesley G, Zhang, Dong-Er |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3721472/ https://www.ncbi.nlm.nih.gov/pubmed/23681607 http://dx.doi.org/10.1002/emmm.201201864 |
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