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Functional genomics identifies five distinct molecular subtypes with clinical relevance and pathways for growth control in epithelial ovarian cancer
Epithelial ovarian cancer (EOC) is hallmarked by a high degree of heterogeneity. To address this heterogeneity, a classification scheme was developed based on gene expression patterns of 1538 tumours. Five, biologically distinct subgroups — Epi-A, Epi-B, Mes, Stem-A and Stem-B — exhibited significan...
Autores principales: | Tan, Tuan Zea, Miow, Qing Hao, Huang, Ruby Yun-Ju, Wong, Meng Kang, Ye, Jieru, Lau, Jieying Amelia, Wu, Meng Chu, Bin Abdul Hadi, Luqman Hakim, Soong, Richie, Choolani, Mahesh, Davidson, Ben, Nesland, Jahn M, Wang, Ling-Zhi, Matsumura, Noriomi, Mandai, Masaki, Konishi, Ikuo, Goh, Boon-Cher, Chang, Jeffrey T, Thiery, Jean Paul, Mori, Seiichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3721473/ https://www.ncbi.nlm.nih.gov/pubmed/23666744 http://dx.doi.org/10.1002/emmm.201201823 |
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