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Modulation of haemodynamics, endogeneous antioxidant enzymes, and pathophysiological changes by selective inhibition of angiotensin II type 1 receptors in pressure-overload rats

BACKGROUND: Constriction of the thoracic or abdominal aorta provides an experimental model of pressure-overload cardiac hypertrophy. Blockade of AT(1) receptors is beneficial in preventing target-organ damage in hypertension. OBJECTIVE: To examine the effect of angiotensin II receptor antagonists on...

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Detalles Bibliográficos
Autores principales: Moinuddin, Ghulam, Inamdar, Mohammed Naseeruddin, Kulkarni, Kala S, Kulkarni, Chanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Clinics Cardive Publishing 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3721829/
https://www.ncbi.nlm.nih.gov/pubmed/23736127
http://dx.doi.org/10.5830/CVJA-2012-080