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Can cardiac surgery be performed safely on patients with haematological malignancies

INTRODUCTION: Surgical strategy in patients with haematological malignancies must be planned and carried out with the specific aim of decreasing postoperative complications. The aim of this study was to present our experience on patients previously diagnosed with haematological malignancies who subs...

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Autores principales: Guler, A, Sahin, MA, Cingoz, F, Ozal, E, Demirkilic, U, Arslan, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Clinics Cardive Publishing 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3721910/
https://www.ncbi.nlm.nih.gov/pubmed/22614661
http://dx.doi.org/10.5830/CVJA-2011-053
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author Guler, A
Sahin, MA
Cingoz, F
Ozal, E
Demirkilic, U
Arslan, M
author_facet Guler, A
Sahin, MA
Cingoz, F
Ozal, E
Demirkilic, U
Arslan, M
author_sort Guler, A
collection PubMed
description INTRODUCTION: Surgical strategy in patients with haematological malignancies must be planned and carried out with the specific aim of decreasing postoperative complications. The aim of this study was to present our experience on patients previously diagnosed with haematological malignancies who subsequently underwent cardiac surgery. We include data to assist other surgeons predict factors affecting postoperative morbidity and mortality in this group of patients. METHODS: Fifteen patients diagnosed with haematological malignancies who had cardiac surgery were retrospectively analysed. Eight patients had chronic lymphocytic leukaemia, six had non-Hodgkin’s lymphoma and the rest had chronic myelocytic leukaemia. Coronary artery bypass graft surgery was performed on all of them. RESULTS: There were no hospital mortalities. The average follow-up period was 35 ± 11 (23–56) months. Three patients required early postoperative re-operation because of excessive bleeding. No mortalities were seen in the early postoperative period. There were five (33%) deaths during the late follow-up period. Three patients were lost due to intracranial bleeding (confirmed by autopsy) in the 16th, 23rd and 38th months after surgery. The remaining two patients had sudden death in the eighth and 55th months from non-detectable causes. CONCLUSION: Conclusion: Cardiac surgery can be performed with acceptable early postoperative outcomes in patients with haematological malignancies. Intracranial bleeding is an important factor contributing to late mortality and patient selection and risk stratification are crucial to improving surgical benefits.
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spelling pubmed-37219102013-08-07 Can cardiac surgery be performed safely on patients with haematological malignancies Guler, A Sahin, MA Cingoz, F Ozal, E Demirkilic, U Arslan, M Cardiovasc J Afr Cardiovascular Topics INTRODUCTION: Surgical strategy in patients with haematological malignancies must be planned and carried out with the specific aim of decreasing postoperative complications. The aim of this study was to present our experience on patients previously diagnosed with haematological malignancies who subsequently underwent cardiac surgery. We include data to assist other surgeons predict factors affecting postoperative morbidity and mortality in this group of patients. METHODS: Fifteen patients diagnosed with haematological malignancies who had cardiac surgery were retrospectively analysed. Eight patients had chronic lymphocytic leukaemia, six had non-Hodgkin’s lymphoma and the rest had chronic myelocytic leukaemia. Coronary artery bypass graft surgery was performed on all of them. RESULTS: There were no hospital mortalities. The average follow-up period was 35 ± 11 (23–56) months. Three patients required early postoperative re-operation because of excessive bleeding. No mortalities were seen in the early postoperative period. There were five (33%) deaths during the late follow-up period. Three patients were lost due to intracranial bleeding (confirmed by autopsy) in the 16th, 23rd and 38th months after surgery. The remaining two patients had sudden death in the eighth and 55th months from non-detectable causes. CONCLUSION: Conclusion: Cardiac surgery can be performed with acceptable early postoperative outcomes in patients with haematological malignancies. Intracranial bleeding is an important factor contributing to late mortality and patient selection and risk stratification are crucial to improving surgical benefits. Clinics Cardive Publishing 2012-05 /pmc/articles/PMC3721910/ /pubmed/22614661 http://dx.doi.org/10.5830/CVJA-2011-053 Text en Copyright © 2010 Clinics Cardive Publishing http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Cardiovascular Topics
Guler, A
Sahin, MA
Cingoz, F
Ozal, E
Demirkilic, U
Arslan, M
Can cardiac surgery be performed safely on patients with haematological malignancies
title Can cardiac surgery be performed safely on patients with haematological malignancies
title_full Can cardiac surgery be performed safely on patients with haematological malignancies
title_fullStr Can cardiac surgery be performed safely on patients with haematological malignancies
title_full_unstemmed Can cardiac surgery be performed safely on patients with haematological malignancies
title_short Can cardiac surgery be performed safely on patients with haematological malignancies
title_sort can cardiac surgery be performed safely on patients with haematological malignancies
topic Cardiovascular Topics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3721910/
https://www.ncbi.nlm.nih.gov/pubmed/22614661
http://dx.doi.org/10.5830/CVJA-2011-053
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