Cargando…

An evaluation of ankle–brachial blood pressure index in adult Nigerians with sickle cell anaemia

AIM: There are few studies to be found in the literature on ankle–brachial index in sickle cell disease. The aim of this study was to compare ankle–brachial index of steady-state adult sickle cell anaemia patients with that of normal controls. METHODS: A descriptive cross-sectional study of 62 sickl...

Descripción completa

Detalles Bibliográficos
Autores principales: Oguanobi, NI, Onwubere, BJC, Ike, SO, Ejim, EC, Ibegbulam, OG, Agwu, O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Clinics Cardive Publishing 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3721938/
https://www.ncbi.nlm.nih.gov/pubmed/22331250
http://dx.doi.org/10.5830/CVJA-2011-013
_version_ 1782278112581517312
author Oguanobi, NI
Onwubere, BJC
Ike, SO
Ejim, EC
Ibegbulam, OG
Agwu, O
author_facet Oguanobi, NI
Onwubere, BJC
Ike, SO
Ejim, EC
Ibegbulam, OG
Agwu, O
author_sort Oguanobi, NI
collection PubMed
description AIM: There are few studies to be found in the literature on ankle–brachial index in sickle cell disease. The aim of this study was to compare ankle–brachial index of steady-state adult sickle cell anaemia patients with that of normal controls. METHODS: A descriptive cross-sectional study of 62 sickle cell anaemia patients and 62 age- and gender-matched normal controls was carried out in the adult outpatient sickle cell clinics and the cardiac centre of the University of Nigeria Teaching Hospital (UNTH), Enugu, Nigeria from February to August 2007. The supine brachial and ankle blood pressures were measured separately with the cuff of the mercury sphygmomanometer applied to the right arm and right calf, respectively. RESULTS: The ankle systolic blood pressure was lower in patients with sickle cell anaemia than in the controls (p < 0.001). The mean indices for ankle–brachial index were 0.88 ± 0.09 and 1.03 ± 0.06, respectively for patients and controls. This difference was statistically significant (p < 0.001). Seventy three per cent of the patients had ankle–brachial index less than 0.9 compared with controls (5%). This was also significant (p < 0.001).
format Online
Article
Text
id pubmed-3721938
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher Clinics Cardive Publishing
record_format MEDLINE/PubMed
spelling pubmed-37219382013-08-07 An evaluation of ankle–brachial blood pressure index in adult Nigerians with sickle cell anaemia Oguanobi, NI Onwubere, BJC Ike, SO Ejim, EC Ibegbulam, OG Agwu, O Cardiovasc J Afr Cardiovascular Topics AIM: There are few studies to be found in the literature on ankle–brachial index in sickle cell disease. The aim of this study was to compare ankle–brachial index of steady-state adult sickle cell anaemia patients with that of normal controls. METHODS: A descriptive cross-sectional study of 62 sickle cell anaemia patients and 62 age- and gender-matched normal controls was carried out in the adult outpatient sickle cell clinics and the cardiac centre of the University of Nigeria Teaching Hospital (UNTH), Enugu, Nigeria from February to August 2007. The supine brachial and ankle blood pressures were measured separately with the cuff of the mercury sphygmomanometer applied to the right arm and right calf, respectively. RESULTS: The ankle systolic blood pressure was lower in patients with sickle cell anaemia than in the controls (p < 0.001). The mean indices for ankle–brachial index were 0.88 ± 0.09 and 1.03 ± 0.06, respectively for patients and controls. This difference was statistically significant (p < 0.001). Seventy three per cent of the patients had ankle–brachial index less than 0.9 compared with controls (5%). This was also significant (p < 0.001). Clinics Cardive Publishing 2012-02 /pmc/articles/PMC3721938/ /pubmed/22331250 http://dx.doi.org/10.5830/CVJA-2011-013 Text en Copyright © 2010 Clinics Cardive Publishing http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Cardiovascular Topics
Oguanobi, NI
Onwubere, BJC
Ike, SO
Ejim, EC
Ibegbulam, OG
Agwu, O
An evaluation of ankle–brachial blood pressure index in adult Nigerians with sickle cell anaemia
title An evaluation of ankle–brachial blood pressure index in adult Nigerians with sickle cell anaemia
title_full An evaluation of ankle–brachial blood pressure index in adult Nigerians with sickle cell anaemia
title_fullStr An evaluation of ankle–brachial blood pressure index in adult Nigerians with sickle cell anaemia
title_full_unstemmed An evaluation of ankle–brachial blood pressure index in adult Nigerians with sickle cell anaemia
title_short An evaluation of ankle–brachial blood pressure index in adult Nigerians with sickle cell anaemia
title_sort evaluation of ankle–brachial blood pressure index in adult nigerians with sickle cell anaemia
topic Cardiovascular Topics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3721938/
https://www.ncbi.nlm.nih.gov/pubmed/22331250
http://dx.doi.org/10.5830/CVJA-2011-013
work_keys_str_mv AT oguanobini anevaluationofanklebrachialbloodpressureindexinadultnigerianswithsicklecellanaemia
AT onwuberebjc anevaluationofanklebrachialbloodpressureindexinadultnigerianswithsicklecellanaemia
AT ikeso anevaluationofanklebrachialbloodpressureindexinadultnigerianswithsicklecellanaemia
AT ejimec anevaluationofanklebrachialbloodpressureindexinadultnigerianswithsicklecellanaemia
AT ibegbulamog anevaluationofanklebrachialbloodpressureindexinadultnigerianswithsicklecellanaemia
AT agwuo anevaluationofanklebrachialbloodpressureindexinadultnigerianswithsicklecellanaemia
AT oguanobini evaluationofanklebrachialbloodpressureindexinadultnigerianswithsicklecellanaemia
AT onwuberebjc evaluationofanklebrachialbloodpressureindexinadultnigerianswithsicklecellanaemia
AT ikeso evaluationofanklebrachialbloodpressureindexinadultnigerianswithsicklecellanaemia
AT ejimec evaluationofanklebrachialbloodpressureindexinadultnigerianswithsicklecellanaemia
AT ibegbulamog evaluationofanklebrachialbloodpressureindexinadultnigerianswithsicklecellanaemia
AT agwuo evaluationofanklebrachialbloodpressureindexinadultnigerianswithsicklecellanaemia